CAS 50866-72-3

D-Streptamine,O-3-amino-3-deoxy-a-D-glucopyranosyl-(1®6)-O-[6-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-6-deoxy-a-D-glucopyranosyl-(1®4)]-2-deoxy-

Description:

D-Streptamine, O-3-amino-3-deoxy-α-D-glucopyranosyl-(1→6)-O-[6-[[(2S)-4-amino-2-hydroxy-1-oxobutyl]amino]-6-deoxy-α-D-glucopyranosyl-(1→4)]-2-deoxy- is a complex aminoglycoside antibiotic. It is characterized by its intricate glycosidic structure, which includes multiple sugar moieties linked through specific glycosidic bonds. This compound exhibits antibacterial properties, primarily by inhibiting protein synthesis in susceptible bacteria, making it effective against a range of Gram-negative and some Gram-positive organisms. The presence of amino and hydroxyl functional groups contributes to its solubility and interaction with bacterial ribosomes. Its stereochemistry, particularly the configuration of the amino acids and sugar units, is crucial for its biological activity. As with many aminoglycosides, it may have potential side effects, including nephrotoxicity and ototoxicity, which necessitate careful monitoring during therapeutic use. Overall, D-streptamine's unique structure and mechanism of action make it a significant compound in the field of antibiotic research and development.

Formula: C₂₂H₄₃N₅O₁₃

Synonyms:

• D-Streptamine,O-3-amino-3-deoxy-a-D-glucopyranosyl-(1® 6)-O-[6-[(4-amino-2-hydroxy-1-oxobutyl)amino]-6-deoxy-a-D-glucopyranosyl-(1® 4)]-2-deoxy-, (S)-
• AntibioticBB-K 6
• Bb-K 6

BB-K 6 Sulfate Salt

Controlled Product

CAS: 50866-72-3

Stability Hygroscopic
Applications BB-K 6 is a semi-synthetic aminoglycoside antibiotic derived from Kanamycin A (K137500).
References Naito, T. et al.: J. Antibiot., 26, 297 (1973); Cron, M.J. et al.: J. Chem. Soc. Chem. Comm., 6, 266 (1979); Nakagawa, S. et al.: Mircob. Drug Resist., 2, 269 (1979);

Formula: C₂₂H₄₃N₅O₁₃·(H₂O₄S)

Color and Shape: White To Off-White

Molecular weight: 585.60 + x(98.08)

Ref: TR-B119100