CAS 509-24-0

Songorine

Description:

Songorine, with the CAS number 509-24-0, is an alkaloid compound primarily derived from certain plant species, particularly those in the family Amaryllidaceae. It is characterized by its complex molecular structure, which includes a bicyclic framework. Songorine exhibits a range of biological activities, including potential anti-inflammatory and analgesic properties, making it of interest in pharmacological research. The compound is typically found in trace amounts in its natural sources, necessitating extraction and purification for study. Its solubility properties can vary, often being more soluble in organic solvents than in water. Additionally, songorine's stability and reactivity can be influenced by environmental factors such as pH and temperature. As with many alkaloids, it may also exhibit toxicity at certain concentrations, highlighting the importance of careful handling and dosage in any applications. Overall, songorine represents a fascinating subject for further investigation in both natural product chemistry and medicinal applications.

Formula: C₂₂H₃₁NO₃

InChI: InChI=1S/C22H31NO3/c1-4-23-10-20(3)6-5-17(25)22-15(20)7-13(18(22)23)21-9-12(11(2)19(21)26)14(24)8-16(21)22/h12-13,15-19,25-26H,2,4-10H2,1,3H3/t12-,13+,15-,16-,17+,18?,19-,20+,21+,22+/m1/s1

InChI key: InChIKey=CBOSLVQFGANWTL-DREQLAFGSA-N

SMILES: O[C@@H]1[C@]23[C@]4([C@@]5([C@@]6(C2(N(CC)C[C@@](C)([C@]3(C6)[H])CC1)[H])[H])C[C@@](C(=O)C4)(C(=C)[C@H]5O)[H])[H]

Synonyms:

• (1R,2R,5R,7R,8R,9R,13R,17R)-11-ethyl-7,16-dihydroxy-13-methyl-6-methylidene-11-azahexacyclo[7.7.2.1~5,8~.0~1,10~.0~2,8~.0~13,17~]nonadecan-4-one (non-preferred name)
• (3R,6S,6aR,6bR,9R,11R,11aR,12R,12aR,14R)-1-Ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-12,3,6a-ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one
• 11-Ethyl-7,16-Dihydroxy-13-Methyl-6-Methylidene-11-Azahexacyclo[7.7.2.1~5,8~.0~1,10~.0~2,8~.0~13,17~]Nonadecan-4-One (Non-Preferred Name)
• 12,3,6a-Ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one, 1-ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-, (3R,6S,6aR,6bR,9R,11R,11aR,12R,12aR,14R)-
• 12,3,6a-Ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one, 1-ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-, [3R-(3α,6β,6aα,6bα,9β,11α,11aβ,12α,12aβ,14R*)]-
• 7,20-Cycloveatchan-12-one, 21-ethyl-1,15-dihydroxy-4-methyl-16-methylene-, (1α,15β)-
• Bullatine G
• Napellonin
• Napellonine
• Songorin
• Xuan-Wu 2
• Zongorine

(3R,6S,6aR,6bR,9R,11R,11aR,12R,12aR,14R)-1-Ethyldodecahydro-6,11-dihydroxy-3-methyl-10-methylene-12,3,6a-ethanylylidene-9,11a-methanoazuleno[2,1-b]azocin-8(9H)-one

CAS: 509-24-0

Formula: C₂₂H₃₁NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 357.4864

Ref: IN-DA00DA55

Songorine

CAS: 509-24-0

Formula: C₂₂H₃₁NO₃

Molecular weight: 357.49

Ref: 7W-GY5428

Songorine

CAS: 509-24-0

Songorine

Purity: ≥95%

Molecular weight: 357.49g/mol

Ref: 54-BUP06177

Songorine

CAS: 509-24-0

Formula: C₂₂H₃₁NO₃

Purity: 95%~99%

Molecular weight: 357.494

Ref: BP-BP0293

Songorine

CAS: 509-24-0

Songorine (Napellonine) shows anti-tumor activity in preliminary pharmacological verification trials including cell proliferation and molecular docking assays.

Formula: C₂₂H₃₁NO₃

Purity: 98% - 99.92%

Color and Shape: Solid

Molecular weight: 357.49

Ref: TM-T5S1882

Songorine

Controlled Product

CAS: 509-24-0

Applications Songorine is an extract from the Aconitum flavum root and may act as an inhibitor of JNK and p53 enhancing stimulation of fibroblast colony/cluster formation and proliferative activity of mesosomal precursors.
References Zyuz'kov, G.et al.: Bull. Exp. Biol. med., 160, 64 (2015);

Formula: C₂₂H₃₁NO₃

Color and Shape: Neat

Molecular weight: 357.49

Ref: TR-S676805

Songorine

CAS: 509-24-0

Songorine is a diterpenoid alkaloid, which is derived from the natural plant genus Aconitum. It primarily acts by interacting with ion channels and modulating neurotransmitter release in the nervous system. This mode of action makes it a compound of interest in the study of neurological pathways and potential neuroprotective effects.

Formula: C₂₂H₃₁NO₃

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 357.49 g/mol

Ref: 3D-FS145273