CAS 509-80-8

Mitraphylline

Description:

Mitraphylline is an alkaloid primarily derived from the leaves of the Mitragyna species, particularly Mitragyna speciosa, commonly known as kratom. It is classified as a tetracyclic oxindole alkaloid and is known for its complex pharmacological profile. Mitraphylline exhibits a range of biological activities, including analgesic, anti-inflammatory, and potential anxiolytic effects. Its mechanism of action is thought to involve interaction with opioid receptors, although it may also influence other neurotransmitter systems. The compound is typically found in the form of a white to off-white crystalline powder and is soluble in organic solvents but has limited solubility in water. Due to its psychoactive properties, mitraphylline has garnered interest in both traditional medicine and modern pharmacology, though its safety profile and long-term effects require further investigation. As with many natural products, the effects can vary based on dosage and individual response, highlighting the importance of cautious use and further research into its therapeutic potential and risks.

Formula: C₂₁H₂₄N₂O₄

InChI: InChI=1/C21H24N2O4/c1-12-14-10-23-8-7-21(16-5-3-4-6-17(16)22-20(21)25)18(23)9-13(14)15(11-27-12)19(24)26-2/h3-6,11-14,18H,7-10H2,1-2H3,(H,22,25)/t12-,13-,14+,18-,21+/m0/s1

InChI key: InChIKey=JMIAZDVHNCCPDM-DAFCLMLCSA-N

SMILES: O=C1[C@@]2([C@]3(N(CC2)C[C@]4([C@](C3)(C(C(OC)=O)=CO[C@H]4C)[H])[H])[H])C=5C(N1)=CC=CC5

Synonyms:

• Ajmalicine oxindole B
• Formosanan-16-carboxylic acid, 19-methyl-2-oxo-, methyl ester, (19α)-
• Methyl (19Alpha)-19-Methyl-2-Oxoformosanan-16-Carboxylate
• Methyl 19alpha-methyl-2-oxoformosanan-16-carboxylate
• Mitraphilline
• Mitraphyllin
• Mitraphylline
• Rubradinin
• Rubradinine
• Spiro[3H-indole-3,6′(4′aH)-[1H]pyrano[3,4-f]indolizine]-4′-carboxylic acid, 1,2,5′,5′a,7′,8′,10′,10′a-octahydro-1′-methyl-2-oxo-, methyl ester, (1′S,3R,4′aS,5′aS,10′aR)-
• Spiro[3H-indole-3,6′(4′aH)-[1H]pyrano[3,4-f]indolizine]-4′-carboxylic acid, 1,2,5′,5′a,7′,8′,10′,10′a-octahydro-1′-methyl-2-oxo-, methyl ester, [1′S-(1′α,4′aα,5′aα,6′β,10′aβ)]-
• methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxo-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate
• (1'S,3R,4'aS,5'aS,10'aR)-1,2,5',5'a,7',8',10',10'a-Octahydro-1'-methyl-2-oxospiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid methyl ester
• 19α-Methyl-2-oxoformosanan-16-carboxylic acid methyl ester
• Spiro[3H-indole-3,6'(4'aH)-[1H]pyrano[3,4-f]indolizine]-4'-carboxylic acid, 1,2,5',5'a,7',8',10',10'a-octahydro-1'-methyl-2-oxo-, methyl ester, (1'S,3R,4'aS,5'aS,10'aR)-
• (1S,4aS,5aS,6R,10aR)-2'-keto-1-methyl-spiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-indoline]-4-carboxylic acid methyl ester
• methyl (1S,4aS,5aS,6R,10aR)-1-methyl-2'-oxospiro[1,4a,5,5a,7,8,10,10a-octahydropyrano[3,4-f]indolizine-6,3'-1H-indole]-4-carboxylate

Mitraphylline

CAS: 509-80-8

Formula: C₂₁H₂₄N₂O₄

Molecular weight: 368.43

Ref: 7W-GY3187

Mitraphylline

CAS: 509-80-8

Mitraphylline

Purity: ≥98%

Molecular weight: 368.43g/mol

Ref: 54-BUP07080

Mitraphylline

CAS: 509-80-8

Formula: C₂₁H₂₄N₂O₄

Purity: 95%~99%

Molecular weight: 368.433

Ref: BP-BP0947

Mitraphylline

CAS: 509-80-8

Formula: C₂₁H₂₄N₂O₄

Molecular weight: 368.43

Ref: 4Z-M-332001

Mitraphylline

CAS: 509-80-8

Mitraphylline inhibits growth in human glioma/neuroblastoma cells and reduces inflammation in neutrophils.

Formula: C₂₁H₂₄N₂O₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 368.43

Ref: TM-TN1933

Mitraphylline

CAS: 509-80-8

Natural alkaloid

Formula: C₂₁H₂₄N₂O₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 368.43

Ref: 5G-89736

Mitraphilline

CAS: 509-80-8

Mitraphilline is an oxindole alkaloid, which is a naturally occurring compound primarily derived from the Uncaria species, particularly Uncaria tomentosa, commonly known as Cat's Claw. This product is sourced from the leaves and bark of the plant, which are rich in a variety of bioactive alkaloids. Mitraphilline's mode of action is primarily associated with its role in modulating the immune system and exhibiting anti-inflammatory and antioxidant properties. At the molecular level, it influences various signaling pathways, potentially offering neuroprotective and cell regulatory benefits.

Formula: C₂₁H₂₄N₂O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 368.43 g/mol

Ref: 3D-FM65481

Mitraphyllin - exact weight protocol

Controlled Product

CAS: 509-80-8

Formula: C₂₁H₂₄N₂O₄

Color and Shape: Neat

Molecular weight: 368.43

Ref: TR-M374000