CAS 509151-65-9

Bombinakinin M

Description:

Bombinakinin M is a peptide derived from the venom of the Bombina orientalis, commonly known as the oriental fire-bellied toad. This substance is characterized by its unique amino acid sequence, which contributes to its biological activity. Bombinakinin M exhibits antimicrobial properties, making it of interest in pharmaceutical research, particularly for developing new antibiotics or antimicrobial agents. Additionally, it may have potential applications in the field of immunology due to its ability to modulate immune responses. The structure of Bombinakinin M typically includes a series of hydrophobic and hydrophilic regions, which influence its interaction with biological membranes and its overall stability. As a peptide, it is sensitive to environmental conditions such as pH and temperature, which can affect its conformation and activity. Research into Bombinakinin M continues to explore its mechanisms of action and potential therapeutic uses, particularly in combating resistant bacterial strains.

Bombinakinin M

CAS: 509151-65-9

Potent, selective bradykinin receptor agonist 50x stronger than bradykinin, contracts guinea pig ileum muscle at EC50 4.0 nM.

Formula: C₁₀₀H₁₅₉N₃₁O₂₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 2179.55

Ref: TM-TP2075

Bombinakinin M tifluoroacetic acid

CAS: 509151-65-9

Bombinakinin M tifluoroacetic acid is an analog of bombinakinin, a peptide hormone that binds to the bradykinin B2 receptor. It has been shown to cause a significant increase in blood pressure in humans and also to bind to the human serum amide receptor. Bombinakinin M tifluoroacetic acid is a potent inhibitor of the enzyme amp-activated protein kinase (AMPK), which regulates cellular energy metabolism. This analog has been shown to inhibit the activity of this enzyme with an IC50 of 0.6 μM. Bombinakinin M tifluoroacetic acid has also been shown to have potential as a tumor suppressor and may be useful for treating cancer, as it inhibits cell growth by inhibiting protein synthesis.

Formula: C₁₀₀H₁₅₉N₃₁O₂₄•(CF₃CO₂H)x

Purity: Min. 95%

Molecular weight: 2,179.5 g/mol

Ref: 3D-JVA15165