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CAS 5094-14-4

:

13,14-Dihydro-15-keto-PGE1

Description:
13,14-Dihydro-15-keto-PGE1, with the CAS number 5094-14-4, is a derivative of prostaglandin E1 (PGE1), which is a naturally occurring lipid compound involved in various physiological processes. This substance is characterized by its structural modifications, specifically the reduction of the double bond between carbons 13 and 14 and the presence of a keto group at carbon 15. These modifications influence its biological activity and stability compared to its parent compound. Prostaglandins, including this derivative, play crucial roles in inflammation, vasodilation, and the regulation of smooth muscle contraction. 13,14-Dihydro-15-keto-PGE1 may exhibit altered pharmacological properties, making it of interest in research related to cardiovascular health, reproductive biology, and potential therapeutic applications. Its solubility, reactivity, and interaction with biological receptors can vary, impacting its efficacy and safety profile in experimental and clinical settings. As with many prostaglandin derivatives, careful consideration of its synthesis, storage, and handling is essential due to its sensitivity to environmental conditions.
Formula:C20H34O5
InChI:InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h16-17,19,23H,2-14H2,1H3,(H,24,25)/t16-,17-,19-/m1/s1
InChI key:InChIKey=CDUVSQMTLOYKTR-ZHALLVOQSA-N
SMILES:C(CCCCCC(O)=O)[C@@H]1[C@@H](CCC(CCCCC)=O)[C@H](O)CC1=O
Synonyms:
  • (11α)-11-Hydroxy-9,15-dioxoprostan-1-oic acid
  • 11α-Hydroxy-9,15-diketoprostanoic acid
  • 11α-Hydroxy-9,15-dioxoprostanoic acid
  • 13,14-Dihydro-15-keto-PGE<sub>1</sub>
  • 13,14-Dihydro-15-ketoprostaglandin E<sub>1</sub>
  • 13,14-Dihydro-15-oxo-PGE<sub>1</sub>
  • 15-Oxodihydroprostaglandin E<sub>1</sub>
  • 15-keto-13,14-Dihydro-PGE<sub>1</sub>
  • 15-keto-13,14-Dihydroprostaglandin E<sub>1</sub>
  • Cyclopentaneheptanoic acid, 3-hydroxy-5-oxo-2-(3-oxooctyl)-
  • See more synonyms
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Found 2 products.
  • 13,14-dihydro-15-keto Prostaglandin E1

    CAS:
    13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1
    Formula:C20H34O5
    Color and Shape:Solid
    Molecular weight:354.48

    Ref: TM-T36147

    1mg
    80.00€
    5mg
    321.00€
    10mg
    572.00€
  • 15-Keto Prostaglandin E0 Dicyclohexylammonium Salt

    Controlled Product
    CAS:

    Applications 15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.
    References Sinzinger, H., et al.: Prostag. Oth. Lipid M., 55, 265 (1998); Ueno, R. PCT Int. Appl. WO 2001005388 A2 20010125. Jan 25, 2001

    Formula:C20H34O5·C12H23N
    Color and Shape:Neat
    Molecular weight:535.8

    Ref: TR-K202056

    10mg
    2,087.00€