CAS 5094-14-4
:13,14-Dihydro-15-keto-PGE1
Description:
13,14-Dihydro-15-keto-PGE1, with the CAS number 5094-14-4, is a derivative of prostaglandin E1 (PGE1), which is a naturally occurring lipid compound involved in various physiological processes. This substance is characterized by its structural modifications, specifically the reduction of the double bond between carbons 13 and 14 and the presence of a keto group at carbon 15. These modifications influence its biological activity and stability compared to its parent compound. Prostaglandins, including this derivative, play crucial roles in inflammation, vasodilation, and the regulation of smooth muscle contraction. 13,14-Dihydro-15-keto-PGE1 may exhibit altered pharmacological properties, making it of interest in research related to cardiovascular health, reproductive biology, and potential therapeutic applications. Its solubility, reactivity, and interaction with biological receptors can vary, impacting its efficacy and safety profile in experimental and clinical settings. As with many prostaglandin derivatives, careful consideration of its synthesis, storage, and handling is essential due to its sensitivity to environmental conditions.
Formula:C20H34O5
InChI:InChI=1S/C20H34O5/c1-2-3-6-9-15(21)12-13-17-16(18(22)14-19(17)23)10-7-4-5-8-11-20(24)25/h16-17,19,23H,2-14H2,1H3,(H,24,25)/t16-,17-,19-/m1/s1
InChI key:InChIKey=CDUVSQMTLOYKTR-ZHALLVOQSA-N
SMILES:C(CCCCCC(O)=O)[C@@H]1[C@@H](CCC(CCCCC)=O)[C@H](O)CC1=O
Synonyms:- (11α)-11-Hydroxy-9,15-dioxoprostan-1-oic acid
- 11α-Hydroxy-9,15-diketoprostanoic acid
- 11α-Hydroxy-9,15-dioxoprostanoic acid
- 13,14-Dihydro-15-keto-PGE<sub>1</sub>
- 13,14-Dihydro-15-ketoprostaglandin E<sub>1</sub>
- 13,14-Dihydro-15-oxo-PGE<sub>1</sub>
- 15-Oxodihydroprostaglandin E<sub>1</sub>
- 15-keto-13,14-Dihydro-PGE<sub>1</sub>
- 15-keto-13,14-Dihydroprostaglandin E<sub>1</sub>
- Cyclopentaneheptanoic acid, 3-hydroxy-5-oxo-2-(3-oxooctyl)-
- Cyclopentaneheptanoic acid, 3-hydroxy-5-oxo-2-(3-oxooctyl)-, stereoisomer
- Dihydro-15-ketoprostaglandin E<sub>1</sub>
- Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11alpha)-
- Prostan-1-oic acid, 11-hydroxy-9,15-dioxo-, (11α)-
- See more synonyms
Sort by
The purity filter is not visible because current products do not have associated purity data for filtering.
Found 2 products.
13,14-dihydro-15-keto Prostaglandin E1
CAS:13,14-dihydro-15-keto Prostaglandin E1 inhibits ADP-induced platelet aggregation in human isolated platelet-rich plasma (IC50=14.8 μg/mL) and is a PGE1Formula:C20H34O5Color and Shape:SolidMolecular weight:354.4815-Keto Prostaglandin E0 Dicyclohexylammonium Salt
CAS:Controlled ProductApplications 15-Keto Prostaglandin E0 is a metabolite of Prostaglandin E1 (P838600) and has been shown to induce arterial thromboresistance in experimental animals and in man, but with several magnitudes higher concentrations than Prostaglandin E1. 15-Keto Prostaglandin E0 is also used as the active ingredient in compositions used for the treatment of external secretion disorders.
References Sinzinger, H., et al.: Prostag. Oth. Lipid M., 55, 265 (1998); Ueno, R. PCT Int. Appl. WO 2001005388 A2 20010125. Jan 25, 2001Formula:C20H34O5·C12H23NColor and Shape:NeatMolecular weight:535.8

