CAS 51-66-1

N-(4-Methoxyphenyl)acetamide

Description:

N-(4-Methoxyphenyl)acetamide, also known as p-Methoxyacetanilide, is an organic compound characterized by its amide functional group attached to a methoxy-substituted phenyl ring. It typically appears as a white to off-white crystalline solid. The compound has a molecular formula that reflects its structure, containing both an acetamide group and a methoxy group, which contribute to its chemical properties. It is moderately soluble in organic solvents like ethanol and ether, but less soluble in water due to its hydrophobic aromatic ring. N-(4-Methoxyphenyl)acetamide is often studied for its potential applications in pharmaceuticals and as an intermediate in organic synthesis. Its properties include a relatively low melting point and stability under standard conditions, although it may undergo hydrolysis in the presence of strong acids or bases. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if ingested or inhaled.

Formula: C₉H₁₁NO₂

InChI: InChI=1S/C9H11NO2/c1-7(11)10-8-3-5-9(12-2)6-4-8/h3-6H,1-2H3,(H,10,11)

InChI key: InChIKey=XVAIDCNLVLTVFM-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC=C(OC)C=C1

Synonyms:

• 4-(Acetylamino)anisole
• 4-Acetamidoanisole
• 4-Acetamidophenyl methyl ether
• 4-Methoxyanilino methyl ketone
• Acetamide, N-(4-methoxyphenyl)-
• Aceto-p-anisidide
• Acetyl-p-anisidine
• Metacetin
• Methacetin
• N-(4-Methoxyphenyl)acetamide
• N-(p-Methoxyphenyl)acetamide
• N-Acetyl-4-methoxyaniline
• N-Acetyl-p-anisidine
• N-Acetyl-p-methoxyaniline
• NSC 4687
• p-Acetanasidine~N-(Methoxyphenyl)acetamide
• p-Acetaniside
• p-Acetanisidide
• p-Acetanisidine
• p-Methoxyacetanilide

p-Acetanisidide

CAS: 51-66-1

Formula: C₉H₁₁NO₂

Purity: >98.0%(HPLC)(N)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 165.19

Ref: 3B-A0019

N-(4-Methoxyphenyl)acetamide

CAS: 51-66-1

Formula: C₉H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 165.1891

Ref: IN-DA003SCX

4'-Methoxyacetanilide

CAS: 51-66-1

4'-Methoxyacetanilide

Formula: C₉H₁₁NO₂

Purity: 98%

Color and Shape: pale purple solid

Molecular weight: 165.19g/mol

Ref: 54-OR4684

4'-Methoxyacetanilide

CAS: 51-66-1

Formula: C₉H₁₁NO₂

Molecular weight: 165.19

Ref: 4Z-A-248013

Methacetin

Controlled Product

CAS: 51-66-1

Applications Methacetin is evaluated in a breath test to predict early liver disfunction due to valproic acid and other cause. Methacetin breath test (MBT) is a rapid, non-invasive assessment of liver function in acute severe liver disease and a potential key tool in future dignosis.
References Dorloechter, L. et al.: Zeitsch. Ernaehrung., 36, 373 (1997); Holtmeier, J. et al.: Sand J. Gastroenterol., 41, 1336 (2006); Lalazar, G. et al.: World J. Gastroenterol., 15, 966 (2009);

Formula: C₉H₁₁NO₂

Color and Shape: Neat

Molecular weight: 165.19

Ref: TR-M258770

Methacetin

CAS: 51-66-1

Methacetin is a chemical compound that is used in the diagnosis of liver impairment. It is a fatty acid and an inhibitor of certain enzymes. Methacetin inhibits the activity of the enzyme acetyl-CoA carboxylase, which catalyzes the conversion of acetyl-CoA to malonyl-CoA, thereby reducing fatty acid synthesis. Methacetin has been shown to be effective in inhibiting the activity of rat liver microsomes at concentrations of 0.01 mM and above. In addition, methacetin has been found to increase the body mass index (BMI) in rats with hepatic impairment and can be used as a biomarker for this condition. Methacetin has been shown to have a molecular docking score of -4.2 kcal/mol when it was docked against human hepatitis B virus (HBV). This indicates that there are strong hydrogen bonding interactions between methacetin and HBV proteins.

Formula: C₉H₁₁NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 165.19 g/mol

Ref: 3D-FM25132

N-(4-Methoxyphenyl)acetamide

CAS: 51-66-1

Formula: C₉H₁₁NO₂

Purity: 98%

Color and Shape: Solid, White to almost white powder

Molecular weight: 165.192

Ref: 10-F091550