CAS 51-83-2

Carbachol

Description:

Carbachol is a synthetic choline ester and a potent agonist of both muscarinic and nicotinic acetylcholine receptors. It is primarily used in pharmacology for its ability to mimic the action of acetylcholine, making it valuable in various medical applications, particularly in ophthalmology for inducing miosis during surgical procedures. Carbachol is characterized by its stability compared to acetylcholine, which is rapidly hydrolyzed in the body. The substance is typically administered as a solution and can be found in various formulations, including eye drops. Its chemical structure features a carbamate group, which contributes to its prolonged action. Carbachol can stimulate smooth muscle contraction and increase secretions in glands, making it useful in treating conditions like glaucoma. However, it may also cause side effects such as bradycardia and gastrointestinal disturbances due to its broad action on the autonomic nervous system. As with any pharmacological agent, its use should be carefully monitored to avoid adverse reactions.

Formula: C₆H₁₅N₂O₂

InChI: InChI=1/C6H14N2O2.ClH/c1-8(2,3)4-5-10-6(7)9;/h4-5H2,1-3H3,(H-,7,9);1H

InChI key: InChIKey=AIXAANGOTKPUOY-UHFFFAOYSA-N

SMILES: C(COC(N)=O)[N+](C)(C)C.[Cl-]

Synonyms:

• (2-Carbamoyloxyethyl)trimethylammonium chloride
• (2-Hydroxyethyl)trimethyl ammonium chloride carbamate
• (2-Hydroxyethyl)trimethylammonium chloride carbamate
• 2-(Trimethylazaniumyl)ethyl carbamate chloride
• 2-(carbamoyloxy)-N,N,N-trimethylethanaminium chloride
• 2-Carbamoyloxyethyltrimethylammonium Chloride
• Carbachol
• Carbachol chloride
• Carbacholin
• Carbacholine
• Carbacholine chloride
• Carbacol
• Carbacolina
• Carbaminocholine chloride
• Carbaminoylcholine chloride
• Carbamiotin
• Carbamoylcholine chloride
• Carbamoylcholine-hydrochloride
• Carbastat Intraocular
• Carbochol
• Carbocholin
• Carbocholine
• Carbyl
• Carcholin
• Choline carbamate chloride
• Choline, chloride, carbamate
• Coletyl
• Doryl
• Doryl (pharmaceutical)
• Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride
• Ethanaminium, 2-[(aminocarbonyl)oxy]-N,N,N-trimethyl-, chloride (1:1)
• Isopto Carbachol
• Jestryl
• Lentin
• Miostat
• Moryl
• Vasoperif
• γ-Carbamoyl choline chloride
• LABOTEST-BB LT00455354
• 2-((aminocarbonyl)oxy)-n,n,n-trimethylethanaminiumchloride
• 2-((aminocarbonyl)oxy)-n,n,n-trimethylethanaminumchloride
• 2-[(aminocarbonyl)oxy]-n,n,n-trimethyl-ethanaminiuchloride
• CARBAMYLCHOLINE CHLORIDE
• carbach
• CHOLINE CHLORIDE CARBAMATER
• 2-((Aminocarbonyl)oxy)-N,N,N-trimethylethanaminium chloride
• 2-[(Aminocarbonyl)oxy]-N,N,N-trimethyle-thanaminiumchloride
• LABOTEST-BB LT00645774
• 2-((aminocarbonyl)oxy)-n,n,n,-trimethyl-ethanaminiuchloride
• 2-(aminocarbonyl)oxy-n,n,n-trimethyl-ethanaminiuchloride
• CARBAMYLCHOLINCHLORIDE

Carbamylcholine Chloride

CAS: 51-83-2

Formula: C₆H₁₅ClN₂O₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 182.65

Ref: 3B-C0596

Carbachol, 98.3%

CAS: 51-83-2

Carbachol, 51-83-2, also known as carbamoylcholine chloride, is a synthetic choline ester which acts as a non-selective cholinergic agonist. Learn more at Thermo Fisher Scientific.

Formula: C₆H₁₅ClN₂O₂

Purity: 98.3%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 182.65

Ref: 02-L06674

CARBACHOL CRS

CAS: 51-83-2

CARBACHOL CRS

Formula: C₆H₁₅ClN₂O₂

Color and Shape: Crystalline Powder. White. Powder.

Molecular weight: 182.6485

Ref: 41-Y0000113

Carbachol

CAS: 51-83-2

Other quaternary ammonium salts and hydroxides

Formula: C₆H₁₅ClN₂O₂

Color and Shape: White Powder

Molecular weight: 182.08221

Ref: 45-1092009

Carbachol

CAS: 51-83-2

Carbachol (Carbamoylcholine chloride), an analog of acetylcholine, serves as a valuable tool in the investigation of various physiological responses mediated by nicotinic (nAChR) and muscarinic (mAChR) acetylcholine receptors. These responses include smooth muscle contraction, gut motility, and neuronal signaling. Known for its agonistic properties, Carbachol activates both nAChR and mAChR, with reported Ki values ranging from 10 to 10,000 nM for different receptor types and experimental preparations.

Formula: C₆H₁₅ClN₂O₂

Purity: >99.99%

Color and Shape: Solid

Molecular weight: 182.65

Ref: TM-T0105

Carbamylcholine chloride

CAS: 51-83-2

Carbamylcholine chloride

Purity: ≥95%

Molecular weight: 182.65g/mol

Ref: 54-OR72791

Carbamoylcholine chloride

CAS: 51-83-2

Formula: C₆H₁₅ClN₂O₂

Purity: (Titration) 98.5 - 101.5 %

Color and Shape: White to off-white crystalline powder

Molecular weight: 182.65

Ref: 7W-GL9772

Carbamoylcholine-d9 Chloride (N,N,N-trimethyl-d9)

CAS: 51-83-2

Purity: 98 atom % D

Molecular weight: 191.70

Ref: 3U-D8235

Carbamoylcholine-d9 Chloride

CAS: 51-83-2

Formula: C₆H₆D₉N₂O₂·Cl

Molecular weight: 156.25 35.45

Ref: 4Z-C-5942

Carbamylcholine Chloride

Controlled Product

CAS: 51-83-2

Stability Hygroscopic
Applications Carbamylcholine Chloride is a cholinergic receptor agonist. Studies show that Carbamylcholine Chloride is resistant to the action of cholinesterases. Carbamylcholine Chloride also displays antiapoptotic effects in cerebellar granule neurons.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Yan, G.M. et al.: Mol. Pharmacol., 47, 248 (1995); Pugh, P.C. et al.: Mol. Cell. Neurosci., 15, 113 (2000);

Formula: C₆H₁₅N₂O₂·Cl

Color and Shape: Neat

Molecular weight: 182.65

Ref: TR-C175970

Carbachol

CAS: 51-83-2

Agonist of muscarinic cholinergic receptors

Formula: C₆H₁₅ClN₂O₂

Color and Shape: White Powder

Molecular weight: 182.65 g/mol

Ref: 3D-FC35133

Carbachol

CAS: 51-83-2

Formula: C₆H₁₅ClN₂O₂

Purity: 99.0%

Molecular weight: 182.082

Ref: 10-F358106