CAS 510-64-5

19-Hydroxyandrostenedione

Description:

19-Hydroxyandrostenedione, with the CAS number 510-64-5, is a steroid hormone that is a derivative of androstenedione. It is characterized by the presence of a hydroxyl group at the 19th carbon position, which distinguishes it from its parent compound. This substance is typically found in the adrenal glands and gonads and plays a role in the biosynthesis of androgens and estrogens. It is a white to off-white crystalline powder that is soluble in organic solvents but has limited solubility in water. The compound is often studied for its potential effects on hormone levels and its implications in various physiological processes, including muscle growth and fat metabolism. In research contexts, 19-hydroxyandrostenedione is sometimes used as a reference standard in assays for steroid hormones. Its biological activity and interactions with steroid receptors make it of interest in endocrinology and sports medicine, particularly regarding its potential use in performance enhancement and its implications in doping regulations.

Formula: C₁₉H₂₆O₃

InChI: InChI=1S/C19H26O3/c1-18-8-7-16-14(15(18)4-5-17(18)22)3-2-12-10-13(21)6-9-19(12,16)11-20/h10,14-16,20H,2-9,11H2,1H3/t14-,15-,16-,18-,19+/m0/s1

InChI key: InChIKey=XGUHPTGEXRHMQQ-BGJMDTOESA-N

SMILES: C(O)[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)C(=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (8Xi,10Xi,13Xi)-19-Hydroxyandrost-4-Ene-3,17-Dione
• 19-Hydroxy-4-Androstene-3,17-Dione
• 19-Hydroxyandrost-4-Ene-3,17-Dione
• 19-Hydroxyandrostendione
• 19-Hydroxyandrostenedione
• 4-Androsten-19-Ol-3,17-Dione
• 4-Androstene-3,17-Dione-19-0L
• 4-Androstene-3,17-Dione-19-Ol
• Androst-4-en-19-ol-3,17-dione
• Androst-4-ene-3,17-dione, 19-hydroxy-
• Androst-4-ene-3,17-dione-19-ol

19-Hydroxy-4-androstene-3,17-dione

CAS: 510-64-5

19-Hydroxy-4-androstene-3,17-dione

Purity: 98%

Molecular weight: 302.41g/mol

Ref: 54-OR1029132

19-Hydroxy-4-androstene-3,17-dione

CAS: 510-64-5

Formula: C₁₉H₂₆O₃

Purity: ≥ 98.0%

Color and Shape: White to off-white or light yellow crystalline powder

Molecular weight: 302.41

Ref: 7W-GE5927

Dienogest Impurity 1

CAS: 510-64-5

Formula: C₁₉H₂₆O₃

Color and Shape: Off-White Solid

Molecular weight: 302.42

Ref: 4Z-D-4221

19-Hydroxyandrost-4-enedione

Controlled Product

CAS: 510-64-5

Formula: C₁₉H₂₆O₃

Color and Shape: Neat

Molecular weight: 302.41

Ref: 04-C14228730

19-Hydroxy-4-androstene-3,17-dione

CAS: 510-64-5

Formula: C₁₉H₂₆O₃

Molecular weight: 302.41

Ref: ST-EA-CP-D37015

Norethindrone Acetate Impurity 5

CAS: 510-64-5

Formula: C₁₉H₂₆O₃

Molecular weight: 302.41

Ref: ST-EA-CP-N52018

19-Hydroxyandrostendione

Controlled Product

CAS: 510-64-5

Applications 19-Hydroxyandrostendione is a novel substituted estrogen as aromatase inhibitor. It induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olactory receptor.
References Polan, M., et al.: J. Clin. Endocrinol. Metab., 70, 480 (1990), Kawasaki, T., et al.: Clin. Exp. Rheumatol., 18, 743, (2000), Castagnetta, L., et al.: Clin. Cancer Res., 8, 3146 (2002); Frontiers in Oncology, May 2018, vol. 8, article 162; https://doi.org/10.3389/fonc.2018.00162; Gen. Eng. and Biotech. News (https://www.genengnews.com/gen-news-highlights/could-prostate-cancer-be-treated-with-aromatherapy-in-the-future/81255862)

Formula: C₁₉H₂₆O₃

Color and Shape: Off White Solid

Molecular weight: 302.41

Ref: TR-H801500

19-Hydroxy-androstene-4-ene-3,17-dione

Controlled Product

CAS: 510-64-5

19-hydroxy-androstene-4-ene-3,17-dione is a metabolite of androstenedione that has been shown to have inhibitory effects on prostate cancer cells. This compound binds to the plasma membrane of these cells, leading to changes in its structure and function. 19-hydoxy-androstene-4-ene-3,17-dione has also been shown to have an inhibitory effect on human chorionic gonadotropin (HCG) and oestrone production by inhibiting the release of luteinizing hormone from the pituitary gland. This compound also inhibits the activity of protein kinase C (PKC), which is important for cell signaling. 19 hydroxyandrostene 4, 17 dione inhibits tissue culture reactions that rely on PKC as well as other enzymes involved in this process.

Formula: C₁₉H₂₆O₃

Purity: Min. 98 Area-%

Color and Shape: Off-White Powder

Molecular weight: 302.41 g/mol

Ref: 3D-FH24307