CAS 51012-32-9

Tiapride

Description:

Tiapride is a medication primarily classified as an atypical antipsychotic and is used mainly for the treatment of various psychiatric disorders, including schizophrenia and certain movement disorders. It acts as a selective dopamine D2 receptor antagonist, which helps to modulate dopaminergic activity in the brain, thereby alleviating symptoms associated with these conditions. Tiapride is known for its relatively low side effect profile compared to other antipsychotics, making it a preferred choice in some cases. The chemical structure of Tiapride includes a thienobenzodiazepine core, contributing to its pharmacological properties. It is typically administered orally and is well-absorbed in the gastrointestinal tract. The substance is also noted for its anxiolytic and muscle relaxant effects, which can be beneficial in treating anxiety-related symptoms. As with any medication, the use of Tiapride should be guided by a healthcare professional, considering potential interactions and contraindications.

Formula: C₁₅H₂₄N₂O₄S

InChI: InChI=1S/C15H24N2O4S/c1-5-17(6-2)10-9-16-15(18)13-11-12(22(4,19)20)7-8-14(13)21-3/h7-8,11H,5-6,9-10H2,1-4H3,(H,16,18)

InChI key: InChIKey=JTVPZMFULRWINT-UHFFFAOYSA-N

SMILES: C(NCCN(CC)CC)(=O)C1=C(OC)C=CC(S(C)(=O)=O)=C1

Synonyms:

• Benzamide, N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)-
• Flc 1374
• Flo 1347
• N,N-diethyl-2-{[2-methoxy-5-(methylsulfonyl)benzoyl]amino}ethanaminium chloride
• N-[2-(diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide
• Thiapride
• Tiaprizal
• TIAPRIDE
• Tiapride

Tiapride Hydrochloride

CAS: 51012-32-9, 51012-33-0

Formula: C₁₅H₂₄N₂O₄S·HCl

Purity: >99.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 364.89

Ref: 3B-T3600

N-[2-(Diethylamino)ethyl]-2-methoxy-5-(methylsulfonyl)benzamide

CAS: 51012-32-9

Formula: C₁₅H₂₄N₂O₄S

Color and Shape: Solid

Molecular weight: 328.4271

Ref: IN-DA00I951

Tiapride

CAS: 51012-32-9

Formula: C₁₅H₂₄N₂O₄S

Color and Shape: White To Off-White Solid

Molecular weight: 328.43

Ref: 4Z-T-286001

Tiapride hydrochloride

CAS: 51012-32-9

Formula: C₁₅H₂₄N₂O₄S·HCl

Purity: 98.5 - 101.0 % (dry basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 364.89

Ref: 7W-GP3857

Tiapride

CAS: 51012-32-9

Tiapride, an atypical neuroleptic, is a selective dopamine D2-receptor antagonist with varying IC50 values for D1-D4.

Formula: C₁₅H₂₄N₂O₄S

Color and Shape: Solid

Molecular weight: 328.43

Ref: TM-T60943

Tiapride

CAS: 51012-32-9

Purity: 98%

Molecular weight: 328.4299927

Ref: 10-F600893

Tiapride

Controlled Product

CAS: 51012-32-9

Applications Tiapride hydrochloride is a D2DR and D3DR inhibitor; Anti-psychotic agent and alternative treatment for Tourette’s syndrome.
References Trawinski, J., et al.: J. Hazard. Mater., 321, 841-858 (2017); Zheng, W., et al.: Hum. Psychopharmacol., 31, 11-18 (2016)

Formula: C₁₅H₂₄N₂O₄S

Color and Shape: Neat

Molecular weight: 328.427

Ref: TR-T437053