CAS 51023-76-8

Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, sodium salt (1:2)

Description:

Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, sodium salt (1:2), with CAS number 51023-76-8, is a synthetic organic compound characterized by its complex structure that includes a sulfonic acid group, an acetylamino group, and an isothiocyanate moiety. This compound is typically soluble in water due to the presence of the sulfonate group, which enhances its ionic character. It exhibits properties that make it useful in various applications, including as a dye or reagent in biochemical assays. The presence of the isothiocyanate group suggests potential reactivity, particularly in nucleophilic substitution reactions, which can be exploited in chemical synthesis. Additionally, the compound may exhibit biological activity, making it of interest in pharmaceutical research. Its stability and reactivity can be influenced by environmental factors such as pH and temperature, which are important considerations in its handling and application. Overall, this compound represents a versatile chemical entity with potential utility in both industrial and research settings.

Formula: C₁₇H₁₄N₂O₇S₃·2Na

InChI: InChI=1S/C17H14N2O7S3.2Na/c1-11(20)19-15-7-5-13(17(9-15)29(24,25)26)3-2-12-4-6-14(18-10-27)8-16(12)28(21,22)23;;/h2-9H,1H3,(H,19,20)(H,21,22,23)(H,24,25,26);;

InChI key: InChIKey=PTNIXKUMMLOEEW-UHFFFAOYSA-N

SMILES: C(=CC1=C(S(=O)(=O)O)C=C(N=C=S)C=C1)C2=C(S(=O)(=O)O)C=C(NC(C)=O)C=C2.[Na]

Synonyms:

• SITS
• Disodium 4-acetamido-4′-isothiocyanatostilbene-2,2′-disulfonate
• Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, disodium salt
• Benzenesulfonic acid, 5-(acetylamino)-2-[2-(4-isothiocyanato-2-sulfophenyl)ethenyl]-, sodium salt (1:2)

Benzenesulfonic acid, 5-​(acetylamino)​-​2-​[2-​(4-​isothiocyanato-​2-​sulfophenyl)​ethenyl]​-​, sodium salt (1:2)

CAS: 51023-76-8

Formula: C₁₇H₁₄N₂NaO₇S₃

Purity: 80%

Color and Shape: Solid

Molecular weight: 477.4870

Ref: IN-DA006UQF

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium

CAS: 51023-76-8

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid disodium, a fluorescent dye, is utilized for retrograde axonal transport demonstration, secondary

Formula: C₁₇H₁₂N₂Na₂O₇S₃

Color and Shape: Solid

Molecular weight: 498.46

Ref: TM-T83326

4-Acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid sodium salt

CAS: 51023-76-8

4-Acetamido-4'-isothiocyanostilbene-2,2'-disulphonic acid sodium salt

Molecular weight: 498.46g/mol

Ref: 54-BIA1213

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic Acid, Sodium Salt

Controlled Product

CAS: 51023-76-8

Stability Hygroscopic, Temperature Sensitive
Applications A fluorescent label for the specific and reversible labelling of the outer components of the plasma membrane. The reagent reacts with a fixed number of sites on the surface of cells concerned with anion permeation; does not pass through the osmotic barrier of the membrane; reacts under physiological conditions of temperature, pH and tonicity; and is detectable in small amounts. SEE ALSO NOTES FOR DIDS (CAT#D460600).Fluorescence: max. Abs. l = 336nm, max. Em. l = 436 nm.
References Maddy., A.H.: Biochim. Biophys. Acta., 88, 390 (1964), Cabantchik, Z.I., et al.: J. Membrane Biol., 10, 311 (1972); Am. J. Physiol. 262, C803 (1992); J. Biol. Chem. 266, 13355 (1991), Ma, W., et al.: J. Pharmacol. Exp. Ther., 328, 409 (2009),

Formula: C₁₇H₁₂N₂O₇S₃·2Na

Color and Shape: Neat

Molecular weight: 498.46

Ref: TR-A158450

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid, sodium salt

CAS: 51023-76-8

4-Acetamido-4'-isothiocyanatostilbene-2,2'-disulfonic acid, sodium salt (AITC-S) is a stilbene derivative with inhibitory properties. It has been shown to inhibit the uptake of camp in rat ventricular myocytes and caco-2 cells as well as the release of camp from rat renal proximal tubules. AITC-S also inhibits the transport of camp into the cells. The mechanism by which AITC-S inhibits uptake is not yet known, but it may be due to competition for a common carrier or an effect on intracellular metabolism. This compound has also been shown to have an acute ischemic protective effect on rats when administered before reperfusion following coronary artery occlusion.

Formula: C₁₇H₁₂N₂Na₂O₇S₃

Purity: Min. 95%

Molecular weight: 498.46 g/mol

Ref: 3D-FA16931