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CAS 51025-85-5

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Arbekacin

Description:
Arbekacin is an aminoglycoside antibiotic primarily used in the treatment of infections caused by Gram-negative bacteria, particularly in cases where other antibiotics may be ineffective due to resistance. It is structurally related to kanamycin and exhibits a broad spectrum of antibacterial activity. Arbekacin works by inhibiting bacterial protein synthesis, leading to cell death. Its mechanism involves binding to the 30S ribosomal subunit, disrupting the translation process. The substance is typically administered intravenously and is known for its effectiveness against certain strains of multidrug-resistant bacteria. Pharmacokinetically, arbekacin is characterized by its distribution in body tissues, with a relatively long half-life, allowing for less frequent dosing. However, like other aminoglycosides, it carries a risk of nephrotoxicity and ototoxicity, necessitating careful monitoring of renal function during treatment. Overall, arbekacin represents a valuable option in the antibiotic arsenal, particularly in the context of rising antibiotic resistance.
Formula:C22H44N6O10
InChI:InChI=1S/C22H44N6O10/c23-4-3-12(30)20(34)28-11-5-10(26)18(37-21-9(25)2-1-8(6-24)35-21)17(33)19(11)38-22-16(32)14(27)15(31)13(7-29)36-22/h8-19,21-22,29-33H,1-7,23-27H2,(H,28,34)/t8-,9+,10-,11+,12-,13+,14-,15+,16+,17-,18+,19-,21+,22+/m0/s1
InChI key:InChIKey=MKKYBZZTJQGVCD-XTCKQBCOSA-N
SMILES:O([C@H]1[C@H](NC([C@H](CCN)O)=O)C[C@H](N)[C@@H](O[C@H]2O[C@H](CN)CC[C@H]2N)[C@@H]1O)[C@H]3O[C@H](CO)[C@@H](O)[C@H](N)[C@H]3O
Synonyms:
  • (2S)-4-amino-N-{(1R,2S,3S,4R,5S)-5-amino-2-[(3-amino-3-deoxy-alpha-D-glucopyranosyl)oxy]-4-[(2,6-diamino-2,3,4,6-tetradeoxy-alpha-D-erythro-hexopyranosyl)oxy]-3-hydroxycyclohexyl}-2-hydroxybutanamide
  • 1-N-[(S)-4-Amino-2-hydroxybutyryl]-3′,4′-dideoxykanamycin B
  • 1665Rb
  • <span class="text-smallcaps">D</smallcap>-Streptamine, O-3-amino-3-deoxy-α-<smallcap>D</smallcap>-glucopyranosyl-(1→6)-O-[2,6-diamino-2,3,4,6-tetradeoxy-α-<smallcap>D</span>-erythro-hexopyranosyl-(1→4)]-N<sup>1</sup>-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deoxy-
  • Ahb-Dkb
  • Arbecacin
  • Arbekacin [INN]
  • Arbekacina
  • Arbekacina [Spanish]
  • Arbekacine
  • See more synonyms
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Found 3 products.
  • Arbekacin

    CAS:
    Arbekacin is an aminoglycoside antibiotic.
    Formula:C22H44N6O10
    Purity:98%
    Color and Shape:Solid
    Molecular weight:552.63

    Ref: TM-T21051

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  • Arbekacin

    CAS:
    Formula:C22H44N6O10
    Molecular weight:552.63

    Ref: 4Z-A-130002

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    10mg
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    25mg
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  • Arbekacin

    CAS:

    Inhibitor of DNA replication; aminoglycoside class

    Formula:C22H44N6O10
    Purity:Min. 95%
    Molecular weight:552.62 g/mol

    Ref: 3D-AA44764

    ne
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