CAS 51037-30-0
:Acipimox
Description:
Acipimox is a pharmaceutical compound primarily used as a lipid-lowering agent, particularly in the management of dyslipidemia. It belongs to the class of drugs known as niacin derivatives and functions by inhibiting the release of free fatty acids from adipose tissue, which subsequently reduces the synthesis of triglycerides and low-density lipoprotein (LDL) cholesterol in the liver. Acipimox is characterized by its ability to improve lipid profiles, thereby reducing the risk of cardiovascular diseases. The compound is typically administered orally and is known for its relatively favorable side effect profile compared to other lipid-lowering agents. Its mechanism of action also includes enhancing the activity of lipoprotein lipase, which aids in the breakdown of triglycerides. Acipimox is often prescribed in conjunction with lifestyle modifications, such as diet and exercise, to achieve optimal therapeutic outcomes. As with any medication, it is important for patients to consult healthcare professionals for appropriate dosing and potential interactions with other medications.
Formula:C6H6N2O3
InChI:InChI=1S/C6H6N2O3/c1-4-2-7-5(6(9)10)3-8(4)11/h2-3H,1H3,(H,9,10)
InChI key:InChIKey=DJQOOSBJCLSSEY-UHFFFAOYSA-N
SMILES:C(O)(=O)C=1C=N(=O)C(C)=CN1
Synonyms:- 2-Pyrazinecarboxylic acid, 5-methyl-, 4-oxide
- 4-Oxo-5-Methylpyrazine-2-Carboxylic Acid
- 5-Methylpyrazine-2-Carboxylic Acid 4-Oxide
- 5-Methylpyrazinecarboxylic acid 4-oxide
- K 9321
- Olbemox
- Olbetam
- Pyrazinecarboxylic acid, 5-methyl-, 4-oxide
- Acipimox
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 13 products.
Acipimox (5-Methylpyrazine-2-carboxylic acid 4-oxide)
CAS:Drugs with nitrogen hetero-atom(s) only, aromatic or modified aromatic, nesoiFormula:C6H6N2O3Color and Shape:Off-White PowderMolecular weight:154.03784Acipimox
CAS:<p>Acipimox (K-9321), a niacin derivative, treats hyperlipidemia in type 2 diabetics.</p>Formula:C6H6N2O3Purity:98.98%Color and Shape:Low Yellow Liquid Or CrystallineMolecular weight:154.125-Methylpyrazine-2-carboxylic Acid 4-Oxide
CAS:Formula:C6H6N2O3Purity:97%Color and Shape:SolidMolecular weight:154.1234Acipimox
CAS:Formula:C6H6N2O3Purity:≥ 98.5%Color and Shape:White to off-white powderMolecular weight:154.12Acipimox
CAS:Formula:C6H6N2O3Purity:>98.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:154.13Acipimox
CAS:Controlled Product<p>Applications Antilipemic.<br>References Fuccella, L.M., et al.: Clin. Pharmacol. Ther., 28, 790 (1980), Lovisolo, P.P., et al.: Pharmacol. Res. Commun., 13, 151 (1981), Aktories, K., et al.: Arzneim.-Forsch., 33, 1525 (1983), Boatman, P., et al.: J. Med. Chem., 51, 7653 (2008), Rigazio, S., et al.: Am. J. Physiol., 295, E413 (2008),<br></p>Formula:C6H6N2O3Color and Shape:YellowMolecular weight:154.12Acipimox - Bio-X ™
CAS:<p>Acipimox is a niacin derivative that is used as a hypolipidemic agent. Acipimox prevents the liver from producing triglycerides and from secreting VLDL, which indirectly results in a slight decrease in LDL and an increase in HDL. Also, it stimulates leptin release and improves insulin sensitivity.</p>Formula:C6H6N2O3Purity:Min. 95%Color and Shape:PowderMolecular weight:154.12 g/mol5-Methylpyrazine-2-carboxylic acid 4-oxide
CAS:<p>Niacin receptor 1 (NIACR1) antagonist; lipid lowering</p>Formula:C6H6N2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:154.12 g/mol5-Carboxy-2-methylpyrazine 1-oxide
CAS:Formula:C6H6N2O3Purity:95%Color and Shape:SolidMolecular weight:154.125
