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CAS 5104-49-4

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Flurbiprofen

Description:
Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Flurbiprofen is typically administered in oral form and is known for its effectiveness in treating conditions such as arthritis, dental pain, and other inflammatory disorders. The substance appears as a white to off-white crystalline powder and is relatively soluble in organic solvents but has limited solubility in water. Its chemical structure includes a propionic acid moiety, which contributes to its pharmacological activity. Flurbiprofen may also exhibit some side effects common to NSAIDs, such as gastrointestinal discomfort, and it is contraindicated in certain populations, including those with specific cardiovascular or gastrointestinal conditions. As with all medications, it is essential to use flurbiprofen under medical supervision to ensure safety and efficacy.
Formula:C15H13FO2
InChI:InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)
InChI key:InChIKey=SYTBZMRGLBWNTM-UHFFFAOYSA-N
SMILES:FC1=C(C=CC(C(C(O)=O)C)=C1)C2=CC=CC=C2
Synonyms:
  • (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
  • (R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
  • (R)-2-Flurbiprofen
  • 1,4-Bis(1,1,1,2,3,3,3-Heptafluoropropan-2-Yl)Benzene
  • 2-(2-Fluoro-1,1'-biphenyl-4-yl)propanoic acid
  • 2-(2-Fluoro-4-biphenyl)propionic acid
  • 2-(2-Fluoro-4-biphenylyl)propanoic acid
  • 2-(2-Fluoro-4-biphenylyl)propionic acid
  • 2-(3-Fluoro-4-phenylphenyl)propanoic acid
  • 2-Fluoro-α-methyl-4-biphenylacetic acid
  • See more synonyms
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