CAS 51077-16-8

N-Boc-(R)-thiazolidine-4-carboxylic acid

Description:

N-Boc-(R)-thiazolidine-4-carboxylic acid is a chiral compound that belongs to the class of thiazolidine derivatives, characterized by the presence of a thiazolidine ring and a carboxylic acid functional group. The "N-Boc" designation indicates that the amine group is protected by a tert-butyloxycarbonyl (Boc) group, which is commonly used in organic synthesis to protect amines during various reactions. This compound is notable for its potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to its ability to act as a building block for more complex molecules. The thiazolidine ring contributes to its structural rigidity and can influence its biological activity. Additionally, the presence of the carboxylic acid group allows for further functionalization and reactivity, making it a versatile intermediate in synthetic pathways. Its chirality (R configuration) is significant in the context of drug development, as the stereochemistry can greatly affect the pharmacological properties of the resulting compounds.

Formula: C₉H₁₅NO₄S

InChI: InChI=1/C9H15NO4S/c1-9(2,3)14-8(13)6-10-5(4-15-6)7(11)12/h5-6,10H,4H2,1-3H3,(H,11,12)

SMILES: CC(C)(C)OC(=O)C1NC(CS1)C(=O)O

Synonyms:

• N-Boc-L-thiaproline
• Boc-Thz-OH
• tert-Butoxycarbonyl-(R)-thiazolidine-4-carboxylic acid
• (4R)-3-(tert-butoxycarbonyl)-1,3-thiazolidine-4-carboxylic acid
• (4S)-3-(tert-butoxycarbonyl)-1,3-thiazolidine-4-carboxylic acid
• 2-(Tert-Butoxycarbonyl)-1,3-Thiazolidine-4-Carboxylic Acid
• Boc-L-Thiazolidine-4-Carboxylic Acid

N-Boc-(R)-(-)-thiazolidine-4-carboxylic acid, 98%

CAS: 51077-16-8

N-Boc-(R)-(-)-thiazolidine-4-carboxylic acid is used as pharmaceutical intermediates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item

Formula: C₉H₁₅NO₄S

Purity: 98%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 233.28

Ref: 02-L19488

Boc-L-thiazolidine-4-carboxylic acid

CAS: 51077-16-8

Boc-Thz-OH has been applied as a masked N-terminal Cys in native chemical ligation. The thioaminal can be cleaved with methoxyamine · HCl.

Formula: C₉H₁₅NO₄S

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 233.29

Ref: 01-4029316

Boc-Thz-OH

CAS: 51077-16-8

Formula: C₉H₁₅NO₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 233.2847

Ref: IN-DA003OHI

(-)-Boc-L-thioproline

CAS: 51077-16-8

Formula: C₉H₁₅NO₄S

Molecular weight: 233.28

Ref: 7W-GM7481

(4R)-3-(tert-Butoxycarbonyl)-1,3-thiazolane-4-carboxylic acid

CAS: 51077-16-8

(4R)-3-(tert-Butoxycarbonyl)-1,3-thiazolane-4-carboxylic acid

Purity: 98%

Molecular weight: 233.28g/mol

Ref: 54-OR8031

(4R)-3-[(tert-butoxy)carbonyl]-1,3-thiazolidine-4-carboxylic acid

CAS: 51077-16-8

Formula: C₉H₁₅NO₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 233.28

Ref: 10-F402230