CAS 51079-10-8

Ethyl α-oxo-1H-indole-3-acetate

Description:

Ethyl α-oxo-1H-indole-3-acetate, with the CAS number 51079-10-8, is a chemical compound that belongs to the class of indole derivatives. It features an indole ring structure, which is a bicyclic compound consisting of a benzene ring fused to a pyrrole ring. The presence of an α-oxo group and an acetate moiety contributes to its reactivity and potential biological activity. This compound is typically characterized by its moderate solubility in organic solvents and may exhibit various functional properties, including potential applications in medicinal chemistry and as a building block in organic synthesis. Ethyl α-oxo-1H-indole-3-acetate may also display interesting pharmacological activities, making it a subject of research in drug development. Its synthesis often involves the use of specific reagents and conditions to ensure the formation of the desired indole structure. As with many organic compounds, safety precautions should be observed when handling this substance, including the use of appropriate personal protective equipment.

Formula: C₁₂H₁₁NO₃

InChI: InChI=1S/C12H11NO3/c1-2-16-12(15)11(14)9-7-13-10-6-4-3-5-8(9)10/h3-7,13H,2H2,1H3

InChI key: InChIKey=WTPMFFQBDYIARF-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)(=O)C=1C=2C(NC1)=CC=CC2

Synonyms:

• 1H-Indole-3-acetic acid, α-oxo-, ethyl ester
• Ethyl 2-(1H-indol-3-yl)-2-oxoacetate
• Ethyl 3-indolylglyoxylate
• Ethyl indole-3-glyoxylate
• Ethyl α-oxo-1H-indole-3-acetate
• Indole-3-glyoxylic acid, ethyl ester
• NSC 402543
• ethyl 1H-indol-3-yl(oxo)acetate

(1H-Indol-3-yl)-oxo-acetic acid ethyl ester

CAS: 51079-10-8

Formula: C₁₂H₁₁NO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 217.2206

Ref: IN-DA00D8IC

Ethyl 2-(1H-indol-3-yl)-2-oxoacetate

CAS: 51079-10-8

Ethyl 2-(1H-indol-3-yl)-2-oxoacetate

Purity: 96%

Molecular weight: 217.22g/mol

Ref: 54-OR96595

Ethyl 2-(indol-3-yl)-2-oxoacetate

CAS: 51079-10-8

Formula: C₁₂H₁₁NO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 217.224

Ref: 10-F050047

Ethyl 2-(indol-3-yl)-2-oxoacetate

CAS: 51079-10-8

Ethyl 2-(indol-3-yl)-2-oxoacetate is a hydroxy derivative of the amino acid tyrosine. It inhibits the enzyme tyrosine hydroxylase, which catalyzes the conversion of tyrosine to L-DOPA. This in turn affects dopamine synthesis and has an inhibitory effect on rat brain. Ethyl 2-(indol-3-yl)-2-oxoacetate also inhibits methylmagnesium borohydride in vitro, which is a reagent that breaks down esters, amides, and nitriles. Tyrosine hydroxylase is inhibited by the presence of two hydroxy groups on the ethyl side chain and one hydroxy group on the indole ring. It can be used as a structural analogue for other drugs that are used to treat Parkinson's disease or depression.

Formula: C₁₂H₁₁NO₃

Purity: Min. 95%

Molecular weight: 217.22 g/mol

Ref: 3D-BCA07910