CAS 511-09-1

Ergocryptine

Description:

Ergocryptine is a naturally occurring alkaloid derived from the ergot fungus, specifically from the species Claviceps purpurea. It belongs to the class of compounds known as ergot alkaloids, which are characterized by their complex tetracyclic structure. Ergocryptine exhibits a range of pharmacological properties, including vasoconstriction and effects on neurotransmitter systems, particularly dopamine. It is often studied for its potential therapeutic applications in treating conditions such as Parkinson's disease and migraine headaches due to its ability to influence dopaminergic activity. The compound is typically administered in its hydrochloride salt form for enhanced solubility and bioavailability. Ergocryptine is known for its relatively low toxicity, but it can cause side effects such as nausea, dizziness, and gastrointestinal disturbances. As with many ergot alkaloids, its use is carefully monitored due to the potential for adverse effects and interactions with other medications. Overall, ergocryptine represents a significant compound in pharmacology, particularly in the context of neurological and vascular health.

Formula: C₃₂H₄₁N₅O₅

InChI: InChI=1S/C32H41N5O5/c1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)4)34-28(38)20-13-22-21-8-6-9-23-27(21)19(15-33-23)14-24(22)35(5)16-20/h6,8-9,13,15,17-18,20,24-26,33,41H,7,10-12,14,16H2,1-5H3,(H,34,38)/t20-,24-,25+,26+,31-,32+/m1/s1

InChI key: InChIKey=YDOTUXAWKBPQJW-NSLWYYNWSA-N

SMILES: O[C@@]12N([C@@H](CC(C)C)C(=O)N3[C@]1(CCC3)[H])C(=O)[C@@](NC(=O)[C@@H]4C=C5C=6C=7C(C[C@]5(N(C)C4)[H])=CNC7C=CC6)([C@@H](C)C)O2

Synonyms:

• (2'Xi,12'Xi)-12'-Hydroxy-5'-(2-Methylpropyl)-3',6',18-Trioxo-2'-(Propan-2-Yl)Ergotaman
• (5'Alpha)-12'-Hydroxy-5'-(2-Methylpropyl)-3',6',18-Trioxo-2'-(Propan-2-Yl)Ergotaman
• (5′α)-12′-Hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)ergotaman-3′,6′,18-trione
• 12'-Hydroxy-5'-(2-Methylpropyl)-3',6',18-Trioxo-2'-(Propan-2-Yl)Ergotaman
• 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv.
• ALPHA-Ergocryptine
• Ergocryptine
• Ergokryptine
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)-, (5′α)-
• Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv.
• NSC 169479
• NSC 407319

Bromocriptine EP Impurity B

CAS: 511-09-1

Formula: C₃₂H₄₁N₅O₅

Color and Shape: Off-White Solid

Molecular weight: 575.71

Ref: 4Z-B-335

Ergocryptine

Controlled Product

CAS: 511-09-1

Formula: C₃₂H₄₁N₅O₅

Color and Shape: Neat

Molecular weight: 575.70

Ref: 04-C13201270

α-Ergocryptine

CAS: 511-09-1

Stability Hygroscopic
Applications α-Ergocryptine is an ergopeptine and one of the ergot alkaloids. An impurity of 2-Bromo α-Ergocryptine Mesylate (B682600).
References Young, J., et al.: J. Environ. Sci. Health, 16, 83 (1981), Sugrue, M., et al.: J. Med. Chem., 40, 2793 (1997),

Formula: C₃₂H₄₁N₅O₅

Color and Shape: Neat

Molecular weight: 575.70

Ref: TR-E597500

Bromocriptine EP Impurity B

CAS: 511-09-1

Formula: C₃₂H₄₁N₅O₅

Molecular weight: 575.71

Ref: ST-EA-CP-B83015

Bromocriptine Mesilate EP Impurity B

CAS: 511-09-1

Formula: C₃₂H₄₁N₅O₅

Molecular weight: 575.71

Ref: ST-EA-CP-B83009

a-Ergocryptine

Controlled Product

CAS: 511-09-1

a-Ergocryptine is an ergot alkaloid derivative, which is a compound sourced from the ergot fungus, particularly *Claviceps purpurea*. Its mode of action involves dopaminergic activity, primarily acting as a dopamine receptor agonist. By binding to dopamine receptors, a-Ergocryptine influences neurotransmitter pathways that regulate various physiological functions.Utilized predominantly in the field of neurology and endocrinology, a-Ergocryptine's applications include the treatment of Parkinson's disease, where it aids in managing symptoms by compensating for dopamine deficiencies. Additionally, it is employed in the control of hyperprolactinemia, effectively reducing elevated prolactin levels, and is sometimes used in addressing menstrual disorders linked to prolactin. Its ability to modulate prolactin and dopamine levels makes it a valuable tool in specific therapeutic protocols. However, its use requires careful medical supervision due to potential side effects and interactions with other medications, emphasizing the need for targeted application within clinical practice.

Formula: C₃₂H₄₁N₅O₅

Purity: Min. 95%

Molecular weight: 575.7 g/mol

Ref: 3D-FE22782