CAS 511-10-4

Ergocryptinine

Description:

Ergocryptinine is a naturally occurring alkaloid derived from the ergot fungus, specifically from the genus Claviceps. It is part of the larger family of ergot alkaloids, which are known for their complex structures and diverse biological activities. Ergocryptinine exhibits a range of pharmacological effects, including vasoconstriction and potential neuroprotective properties. It interacts with various neurotransmitter receptors, particularly those associated with serotonin and dopamine, which may contribute to its effects on the central nervous system. The compound is characterized by its unique tetracyclic structure, which includes a fused indole and isoquinoline moiety. Ergocryptinine has been studied for its potential therapeutic applications, although its use is limited due to the side effects associated with ergot alkaloids, such as nausea and vasospasm. As with many alkaloids, the safety and efficacy of ergocryptinine depend on dosage and individual response, necessitating careful consideration in any therapeutic context.

Formula: C₃₂H₄₁N₅O₅

InChI: InChI=1S/C32H41N5O5/c1-17(2)12-25-29(39)36-11-7-10-26(36)32(41)37(25)30(40)31(42-32,18(3)4)34-28(38)20-13-22-21-8-6-9-23-27(21)19(15-33-23)14-24(22)35(5)16-20/h6,8-9,13,15,17-18,20,24-26,33,41H,7,10-12,14,16H2,1-5H3,(H,34,38)/t20-,24+,25-,26-,31+,32-/m0/s1

InChI key: InChIKey=YDOTUXAWKBPQJW-JJANYQHSSA-N

SMILES: O[C@@]12N([C@@H](CC(C)C)C(=O)N3[C@]1(CCC3)[H])C(=O)[C@@](NC(=O)[C@H]4C=C5C=6C=7C(C[C@]5(N(C)C4)[H])=CNC7C=CC6)([C@@H](C)C)O2

Synonyms:

• (5Alpha,5'Beta)-12'-Hydroxy-5'-(2-Methylpropyl)-3',6',18-Trioxo-2'-(Propan-2-Yl)Ergotaman
• (5′α,8α)-12′-Hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)ergotaman-3′,6′,18-trione
• (8alpha)-12'-Hydroxy-5'alpha-isobutyl-2'-isopropylergotaman-3',6',18-trione
• 8H-Oxazolo[3,2-a]pyrrolo[2,1-c]pyrazine, ergotaman-3′,6′,18-trione deriv.
• Ergocryptinine
• Ergokryptinine
• Ergotaman-3',6',18-trione, 12'-hydroxy-2'-(1-methylethyl)-5'-(2-methylpropyl)-, (5'alpha,8alpha)-
• Ergotaman-3′,6′,18-trione, 12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)-, (5′α,8α)-
• Indolo[4,3-fg]quinoline, ergotaman-3′,6′,18-trione deriv.
• Isoergokryptine
• α-Ergocryptinine

Ergocryptinine

Controlled Product

CAS: 511-10-4

Formula: C₃₄H₅₈OSi

Color and Shape: Neat

Molecular weight: 510.91

Ref: 04-C13201275

Ergocryptinine

CAS: 511-10-4

Formula: C₃₂H₄₁N₅O₅

Molecular weight: 575.71

Ref: 4Z-E-231001

Alpha-Ergocryptinine (contains up to 10% Ethyl Acetate)

Controlled Product

CAS: 511-10-4

Applications Ergot alkaloids.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Kantorova, M. et al.: J. Nat. Prod. 65, 1039 (2002); Rotter, R. et al.: Can. J. Anim. Sci. 65, 953 (1985)

Formula: C₃₄H₅₈OSi

Color and Shape: Neat

Molecular weight: 510.91

Ref: TR-E597520

α-Ergocryptinine-d3

Controlled Product

CAS: 511-10-4

Formula: C₃₂D₃H₃₈N₅O₅

Color and Shape: Neat

Molecular weight: 578.717

Ref: TR-E597522

a-Ergocryptinine - contains up to 10% ethyl acetate

Controlled Product

CAS: 511-10-4

Ergocryptine is a drug that is used in the treatment of inflammatory diseases. It is an analog of ergocryptine and contains up to 10% ethyl acetate. Ergocryptine inhibits the production of various cytokines, such as tumor necrosis factor-α (TNF-α), and reduces the infiltration of inflammatory cells into tissues. This drug has been shown to reduce restenosis rates in animal studies. Ergocryptine has also been shown to inhibit matrix metalloproteinases (MMP) activity and expression, which may contribute to its anti-inflammatory effects.

Formula: C₃₂H₄₁N₅O₅

Purity: Min. 95%

Molecular weight: 575.7 g/mol

Ref: 3D-FE22783