CAS 511-13-7

Chlophedianol hydrochloride

Description:

Chlophedianol hydrochloride is a synthetic compound primarily used as a cough suppressant and is classified as an antitussive agent. It is a white to off-white crystalline powder that is soluble in water and exhibits a moderate stability profile under standard conditions. The chemical structure of Chlophedianol hydrochloride features a phenolic group, which contributes to its pharmacological activity. It acts by suppressing the cough reflex in the central nervous system, making it effective in treating cough associated with various respiratory conditions. The compound is typically administered in oral formulations and is known for its relatively low toxicity profile when used as directed. However, like many medications, it may have side effects, including drowsiness or gastrointestinal disturbances. Due to its pharmacological properties, Chlophedianol hydrochloride is often included in combination cough and cold medications. As with any pharmaceutical agent, it is essential to use it under medical supervision to avoid potential interactions and ensure appropriate dosing.

Formula: C₁₇H₂₀ClNO·ClH

InChI: InChI=1S/C17H20ClNO.ClH/c1-19(2)13-12-17(20,14-8-4-3-5-9-14)15-10-6-7-11-16(15)18;/h3-11,20H,12-13H2,1-2H3;1H

InChI key: InChIKey=XYGSFNHCFFAJPO-UHFFFAOYSA-N

SMILES: C(CCN(C)C)(O)(C1=C(Cl)C=CC=C1)C2=CC=CC=C2.Cl

Synonyms:

• 1-(2-Chlorophenyl)-3-(Dimethylamino)-1-Phenylpropan-1-Ol
• 1-(2-Chlorophenyl)-3-(Dimethylamino)-1-Phenylpropan-1-Ol Hydrochloride (1:1)
• 1-(2-Chlorophenyl)-3-(dimethylamino)-1-phenylpropan-1-ol hydrochloride
• 1-o-Chlorophenyl-1-phenyl-3-dimethylamino-1-propanol hydrochloride
• 2-Chloro-α-[2-(dimethylamino)ethyl]benzhydrol hydrochloride
• Benzenemethanol, 2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl-, hydrochloride
• Benzenemethanol, 2-chloro-α-[2-(dimethylamino)ethyl]-α-phenyl-, hydrochloride (1:1)
• Benzhydrol, 2-chloro-α-[2-(dimethylamino)ethyl]-, hydrochloride
• Clofedanol Hydrochloride
• Coldrin
• Detigon
• Pectolitan
• Refugal
• Sk 74
• Sl 501
• Ulone
• α-(2-Dimethylaminoethyl)-o-chlorobenzhydrol hydrochloride

Clofedanol HCl

CAS: 511-13-7

Formula: C₁₇H₂₀ClNO·HCl

Color and Shape: White To Off-White Solid

Molecular weight: 289.80 36.46

Ref: 4Z-C-336001

Clofedanol Hydrochloride

Controlled Product

CAS: 511-13-7

Stability Hygroscopic
Applications A centrally-acting cough suppressant. It has local anesthetic and antihistamine properties, and may have anticholinergic effects at high doses.
References Yuizono, T., et al.: Yakugaku Zasshi, 87, 915 (1967), Nomura, A., et al.: Oyo Yakuri, 8, 119 (1974),

Formula: C₁₇H₂₀ClNO·ClH

Color and Shape: White To Off-White

Molecular weight: 326.26

Ref: TR-C586920

Chlophedianol Hydrochloride

CAS: 511-13-7

Chlophedianol hydrochloride: a cough suppressant for dry cough with antihistamine and local anesthetic traits; possibly anticholinergic at high doses.

Formula: C₁₇H₂₁Cl₂NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 326.26

Ref: TM-T21372