CAS 51103-57-2

[(3R,4R,4aR,6aS,8R,9S,11bS)-3,9-dihydroxy-4-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-9-yl]methyl acetate

Description:

The chemical substance with the name "[(3R,4R,4aR,6aS,8R,9S,11bS)-3,9-dihydroxy-4-(hydroxymethyl)-4,11b-dimethyltetradecahydro-8,11a-methanocyclohepta[a]naphthalen-9-yl]methyl acetate" and CAS number "51103-57-2" is a complex organic compound characterized by its intricate stereochemistry and multiple functional groups. It features a tetradecahydro structure, indicating a saturated cyclic system, and contains hydroxyl groups that suggest potential for hydrogen bonding and reactivity. The presence of a methyl acetate moiety implies that it can undergo esterification reactions, making it relevant in organic synthesis. This compound may exhibit biological activity due to its structural features, which could interact with biological systems. Its stereochemical configuration indicates specific spatial arrangements of atoms, which can significantly influence its chemical behavior and interactions. Overall, this substance is of interest in fields such as medicinal chemistry and organic synthesis, where its unique properties may be harnessed for various applications.

Formula: C₂₂H₃₆O₅

InChI: InChI=1/C22H36O5/c1-14(24)27-13-22(26)9-8-21-11-16(22)10-15(21)4-5-17-19(2,12-23)18(25)6-7-20(17,21)3/h15-18,23,25-26H,4-13H2,1-3H3/t15-,16+,17-,18+,19-,20-,21?,22+/m0/s1

Aphidicolin 17-acetate

CAS: 51103-57-2

Aphidicolin 17-acetate is a selective inhibitor of eukaryotic DNA polymerase α (DNA polymeraseα) that does not inhibit DNA polymerases β and γ. It significantly suppresses DNA synthesis in sea urchin embryos and HeLa cells in vivo without affecting RNA and protein synthesis.

Formula: C₂₂H₃₆O₅

Color and Shape: Solid

Molecular weight: 380.518

Ref: TM-TN9020

Aphidicolin 17-acetate

CAS: 51103-57-2

Formula: C₂₂H₃₆O₅

Molecular weight: 380.5

Ref: 7W-GL1264

Aphidicolin 17-acetate

CAS: 51103-57-2

Aphidicolin 17-acetate is a chemical compound that acts as a potent inhibitor of DNA polymerase. It is derived from the fungus Cephalosporium aphidicola. This compound functions by selectively inhibiting DNA polymerase α, which is crucial for DNA replication. Its action leads to the blockage of the S-phase of the cell cycle, thereby preventing DNA synthesis and cell division.

Formula: C₂₂H₃₆O₅

Purity: Min. 95%

Molecular weight: 380.50 g/mol

Ref: 3D-BCA10357