CAS 5111-65-9

2-Bromo-6-methoxynaphthalene

Description:

2-Bromo-6-methoxynaphthalene is an organic compound characterized by its naphthalene backbone, which consists of two fused benzene rings. The presence of a bromine atom at the 2-position and a methoxy group (-OCH3) at the 6-position contributes to its unique chemical properties. This compound typically appears as a solid at room temperature and is known for its moderate solubility in organic solvents such as ethanol and dichloromethane, while being less soluble in water. The bromine substituent enhances its reactivity, making it useful in various chemical reactions, including nucleophilic substitutions and cross-coupling reactions. The methoxy group can influence the electronic properties of the molecule, affecting its reactivity and interaction with other chemical species. 2-Bromo-6-methoxynaphthalene is often utilized in organic synthesis and materials science, particularly in the development of pharmaceuticals and agrochemicals. As with many brominated compounds, it is essential to handle it with care due to potential environmental and health impacts.

Formula: C₁₁H₉BrO

InChI: InChI=1S/C11H9BrO/c1-13-11-5-3-8-6-10(12)4-2-9(8)7-11/h2-7H,1H3

InChI key: InChIKey=AYFJBMBVXWNYLT-UHFFFAOYSA-N

SMILES: O(C)C1=CC2=C(C=C(Br)C=C2)C=C1

Synonyms:

• (6-Brom-2-Naphthyl)-Methyl Ether
• 2-Bromo-6-Methoxy Napthalene
• 2-Bromo-6-Methoxynapthalene
• 2-Methoxy-6-bromonaphthalene
• 6-Bromo-2-Methoxynaphthalene
• 6-Bromo-2-Naphthyl Methyl Ether
• 6-Bromo-2-methyl-naphthalene
• 6-Methoxy-2-Bromo Naphthalene
• 6-Methoxy-2-bromonaphthalene
• 6-Methoxynaphth-2-yl bromide
• BMN
• Bromo(2-)-6-Methoxy Naphthalene
• NSC 3236
• Naphthalene, 2-bromo-6-methoxy-

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 237.10

Ref: 3B-B1547

2-Bromo-6-methoxynaphthalene, 98%

CAS: 5111-65-9

2-Bromo-6-methoxynaphthalene is used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy bra

Formula: C₁₁H₉BrO

Purity: 98%

Color and Shape: White to cream or pale pink, Powder

Molecular weight: 237.10

Ref: 02-A19450

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

2-Bromo-6-methoxynaphthalene was used in the synthesis of nabumetone [4-(6-methoxy-2-naphthalenyl)-2-butanone] by Heck reaction.

Formula: C₁₁H₉BrO

Purity: 98.51%

Color and Shape: White To Off-White Powder

Molecular weight: 237.09

Ref: TM-T0663

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Purity: 97%

Color and Shape: Solid

Molecular weight: 237.0926

Ref: IN-DA003GQZ

Naproxen EP Impurity N

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Color and Shape: Off-White Solid

Molecular weight: 237.10

Ref: 4Z-N-2317

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

2-Bromo-6-methoxynaphthalene

Purity: ≥98%

Molecular weight: 237.09g/mol

Ref: 54-BUP19179

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

2-Bromo-6-methoxynaphthalene

Formula: C₁₁H₉BrO

Purity: 97%

Color and Shape: faint brown powder

Molecular weight: 237.09g/mol

Ref: 54-OR28828

2-Bromo-6-methoxynaphthalene

Controlled Product

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Color and Shape: Neat

Molecular weight: 237.09

Ref: 86-MM0152.17

2-Bromo-6-methoxynaphthalene (Naproxen Impurity N)

CAS: 5111-65-9

Impurity Naproxen EP Impurity N
Applications Naproxen Impurity N.
References Markku, A., et al.: J. Pharm. Sci., 66, 433 (1977), Hamai, S., et al.: J. Phys. Chem., 99, 12109 (1995), Kearney, P., et al.: Br. Med. J., 332, 1302 (2006),

Formula: C₁₁H₉BrO

Color and Shape: White

Molecular weight: 237.09

Ref: TR-B684780

Naproxen EP Impurity N

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Molecular weight: 237.10

Ref: ST-EA-CP-N2014

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

2-Bromo-6-methoxynaphthalene (BMN) is a palladium complex with a methyl group at the 2-position, which can be synthesized by cross-coupling of an aryl halide and a hydroxyl group. The synthesis reaction is conducted in solution and the final product can be isolated by distillation. BMN has potent inhibitory activity against cervical cancer cells. It inhibits DNA synthesis by competing with other molecules for binding to the active site on topoisomerase II. This drug also inhibits the production of RNA and protein, which may be due to its ability to bind to ribosomes in eukaryotic cells.

Formula: C₁₁H₉BrO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 237.09 g/mol

Ref: 3D-FB00553

2-Bromo-6-methoxynaphthalene

CAS: 5111-65-9

Formula: C₁₁H₉BrO

Purity: 97%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 237.096

Ref: 10-F023276