CAS 51114-94-4

Phosphonium, (2-carboxyethyl)triphenyl-, bromide (1:1)

Description:

Phosphonium, (2-carboxyethyl)triphenyl-, bromide (1:1) is a quaternary ammonium compound characterized by a positively charged phosphonium ion and a bromide counterion. This substance features a triphenylphosphonium core, which is known for its lipophilicity and ability to penetrate biological membranes. The presence of the 2-carboxyethyl group introduces a polar functional group, enhancing its solubility in polar solvents and potentially influencing its reactivity and biological interactions. As a bromide salt, it is typically stable under standard conditions but may undergo hydrolysis or other reactions in the presence of strong nucleophiles or under acidic or basic conditions. Phosphonium compounds are often utilized in organic synthesis, particularly in the formation of phosphonium ylides, which are valuable intermediates in the synthesis of various organic compounds. Additionally, due to their unique properties, they may find applications in medicinal chemistry and materials science. Safety data should be consulted for handling and storage, as with all chemical substances.

Formula: C₂₁H₂₀O₂P·Br

InChI: InChI=1S/C21H19O2P.BrH/c22-21(23)16-17-24(18-10-4-1-5-11-18,19-12-6-2-7-13-19)20-14-8-3-9-15-20;/h1-15H,16-17H2;1H

InChI key: InChIKey=BVKRDNIULHRLCO-UHFFFAOYSA-N

SMILES: [P+](CCC(O)=O)(C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3.[Br-]

Synonyms:

• (2-Carboxyethyl)(triphenyl)phosphonium bromide
• (β-Carboxyethyl)triphenylphosphonium bromide
• 3-(Triphenylphosphonium)propionic acid bromide
• NSC 84145
• Phosphonium, (2-Carboxyethyl)Triphenyl-, Bromide (1:1)
• Phosphonium, (2-carboxyethyl)triphenyl-, bromide
• (2-Carboxyethyl)triphenylphosphonium bromide

(2-Carboxyethyl)triphenylphosphonium Bromide

CAS: 51114-94-4

Formula: C₂₁H₂₀BrO₂P

Purity: >96.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 415.27

Ref: 3B-C3309

(2-CARBOXYETHYL)TRIPHENYLPHOSPHONIUM BROMIDE

CAS: 51114-94-4

Formula: C₂₁H₂₀BrO₂P

Purity: 97%

Color and Shape: Solid

Molecular weight: 415.2601

Ref: IN-DA0037QR

(2-Carboxyethyl)(triphenyl)phosphonium bromide

CAS: 51114-94-4

(2-Carboxyethyl)(triphenyl)phosphonium bromide

Formula: C₂₁H₂₀O₂P·Br

Purity: 97%

Color and Shape: white solid

Molecular weight: 415.26g/mol

Ref: 54-OR18825

(2-Carboxyethyl)triphenylphosphonium bromide

CAS: 51114-94-4

Purity: 98%

Color and Shape: Solid

Molecular weight: 415.27

Ref: 10-F788815

2-Carboxyethyl(triphenyl)phosphonium bromide

CAS: 51114-94-4

2-Carboxyethyl(triphenyl)phosphonium bromide is a phosphonium salt that inhibits the adenosine receptors. It is also shown to have anti-cancer effects on cells. 2-Carboxyethyl(triphenyl)phosphonium bromide has been shown to inhibit the growth of cancer cells in cell culture and in animal models. It has been proposed as a potential therapeutic agent for neurodegenerative diseases, such as Parkinson's disease and Huntington's disease, due to its ability to inhibit the activity of the enzyme formylation. The drug binds to nucleophilic sites on proteins, which may be due to its structure activity relationship with adenosine receptors. The synthesis of this drug involves ethyl formate as a starting material, which undergoes an amination reaction with diisobutylaluminium followed by formylation with dibromomethane in acid catalyst conditions.

Formula: C₂₁H₂₀O₂PBr

Purity: Min. 95%

Molecular weight: 415.26 g/mol

Ref: 3D-BCA11494