CAS 51146-55-5

Hydroxyibuprofen

Description:

Hydroxyibuprofen, with the CAS number 51146-55-5, is a derivative of ibuprofen, a widely used nonsteroidal anti-inflammatory drug (NSAID). This compound exhibits anti-inflammatory, analgesic, and antipyretic properties, making it effective in alleviating pain, reducing inflammation, and lowering fever. Hydroxyibuprofen is characterized by the presence of a hydroxyl group (-OH) that enhances its solubility and bioavailability compared to its parent compound, ibuprofen. The molecular structure typically includes a propionic acid moiety, which is common among NSAIDs, contributing to its mechanism of action through the inhibition of cyclooxygenase enzymes (COX-1 and COX-2). This inhibition leads to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. Hydroxyibuprofen is often studied for its potential therapeutic benefits and may be utilized in various formulations, including topical applications and oral medications. As with other NSAIDs, it is important to consider potential side effects and contraindications when using hydroxyibuprofen, particularly in individuals with certain health conditions.

Formula: C₁₃H₁₈O₃

InChI: InChI=1S/C13H18O3/c1-9(12(14)15)11-6-4-10(5-7-11)8-13(2,3)16/h4-7,9,16H,8H2,1-3H3,(H,14,15)

InChI key: InChIKey=UJHKVYPPCJBOSG-UHFFFAOYSA-N

SMILES: C(C(C)(C)O)C1=CC=C(C(C(O)=O)C)C=C1

Synonyms:

• Hydroxyibuprofen
• 2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propionic acid
• 4-(2-Hydroxy-2-methylpropyl)-α-methylbenzeneacetic acid
• Benzeneacetic acid, 4-(2-hydroxy-2-methylpropyl)-α-methyl-
• 2,4′-(2-Hydroxy-2-methylpropyl)phenylpropionic acid

2-[4-(2-HYDROXY-2-METHYLPROPYL)PHENYL]PROPIONIC ACID

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 222.2802

Ref: IN-DA00DANE

2-(4-(2-Hydroxy-2-Methylpropyl)Phenyl)Propanoic Acid

CAS: 51146-55-5

2-(4-(2-Hydroxy-2-Methylpropyl)Phenyl)Propanoic Acid

Purity: 95%

Molecular weight: 222.28g/mol

Ref: 54-OR1023995

Ibuprofen-2-hydroxy

Controlled Product

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Color and Shape: Neat

Molecular weight: 222.28

Ref: 04-C14278160

2-[4-(2-Hydroxy-2-methylpropyl)phenyl]propanoic Acid (2-Hydroxyibuprofen)

Controlled Product

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Color and Shape: Neat

Molecular weight: 222.28

Ref: 86-MM0002.32

2-Hydroxy Ibuprofen

CAS: 51146-55-5

2-Hydroxy Ibuprofen is a metabolite of ibuprofen, applicable in biochemical experiments and drug synthesis research. Ibuprofen inhibits both COX-1 and COX-2.

Formula: C₁₃H₁₈O₃

Color and Shape: Solid

Molecular weight: 222.28

Ref: TM-T10072

Ibuprofen-2-hydroxy 100 µg/mL in Acetonitrile

Controlled Product

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Color and Shape: Single Solution

Molecular weight: 222.28

Ref: 04-A14278160AL-100

2-Hydroxyibuprofen

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Molecular weight: 222.29

Ref: 4Z-I-0428

2-Hydroxyibuprofen-d3

CAS: 51146-55-5

Formula: C₁₃H₁₅D₃O₃

Molecular weight: 225.30

Ref: 4Z-I-0481

rac 2-Hydroxy Ibuprofen

Controlled Product

CAS: 51146-55-5

Applications A human metabolite of Ibuprofen.
References Bales, J., et al.: Clin. Chem., 31, 757 (1985), Maurer, H., et al.: J. Anal. Toxicol., 25, 237 (2001), Zwiener, C., et al.: Anal. Bioanal. Chem., 372, 569 ( 2002), de Bernardi, B., et al.: J. Clin. Oncol., 21, 1592 (2003),

Formula: C₁₃H₁₈O₃

Color and Shape: Off-White

Molecular weight: 222.28

Ref: TR-H942860

Rac 2-Hydroxy Ibuprofen

CAS: 51146-55-5

Formula: C₁₃H₁₈O₃

Molecular weight: 222.28

Ref: ST-EA-CP-I2047