CAS 51146-57-7
:(-)-Ibuprofen
Description:
(-)-Ibuprofen, with the CAS number 51146-57-7, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for its analgesic, antipyretic, and anti-inflammatory properties. It is characterized by its chiral structure, with the (-) enantiomer being the active form that exhibits therapeutic effects. The molecular formula of ibuprofen is C13H18O2, and it features a propionic acid moiety, which contributes to its ability to inhibit cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins involved in pain and inflammation. (-)-Ibuprofen is typically administered orally and is available in various formulations, including tablets, capsules, and suspensions. It is known for its relatively rapid onset of action and is often used to relieve mild to moderate pain, such as headaches, menstrual cramps, and muscle aches. While generally well-tolerated, it can cause gastrointestinal side effects and should be used with caution in individuals with certain health conditions. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are important for determining dosing regimens.
Formula:C13H18O2
InChI:InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m1/s1
InChI key:InChIKey=HEFNNWSXXWATRW-SNVBAGLBSA-N
SMILES:[C@@H](C(O)=O)(C)C1=CC=C(CC(C)C)C=C1
Synonyms:- (-)-Ibuprofen
- (-)-Ibuprophen
- (-)-α-Methyl-4-(2-methylpropyl)benzeneacetic acid
- (2R)-2-(4-Isobutylphenyl)propanoic acid
- (R)-(-)-Ibuprofen
- (R)-2-(4-Isobutylphenyl)propanoic acid
- (αR)-α-Methyl-4-(2-methylpropyl)benzeneacetic acid
- Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (R)-
- Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (αR)-
- R-(-)-p-Isobutylhydratropic acid
- benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, (alphaR)-
- See more synonyms
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 11 products.
(R)-2-(4-Isobutylphenyl)Propanoic Acid
CAS:(R)-2-(4-Isobutylphenyl)Propanoic AcidPurity:98%Molecular weight:206.28g/mol(R)-(-)-Ibuprofen
CAS:(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.Formula:C13H18O2Purity:99.86%Color and Shape:SolidMolecular weight:206.28(R)-(-)-Ibuprofen
CAS:Formula:C13H18O2Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:206.29(R)-(-)-Ibuprofen
CAS:Controlled Product<p>Applications A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.<br>References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),<br></p>Formula:C13H18O2Color and Shape:White SolidMolecular weight:206.28(R)-(-)-Ibuprofen
CAS:<p>Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation. It belongs to the group of fatty acid derivatives, which are drugs that block the production of prostaglandins. Ibuprofen has been shown to have contraceptive effects in humans and experimental models, as well as an effect on human serum lipoproteins. Ibuprofen has also been shown to inhibit the synthesis of prostaglandins in rat liver microsomes and asymmetric synthesis in wastewater treatment. Its pharmacokinetic properties are determined by its absorption rate, distribution volume, and metabolism rate. The kinetic behavior of ibuprofen is affected by matrix effect and the kinetic behavior of ibuprofen is also affected by its pharmacokinetic properties such as isooctane, carcinoma cell lines, etc.</p>Formula:C13H18O2Purity:Min. 95%Color and Shape:White PowderMolecular weight:206.28 g/mol
