CAS 51146-57-7

(-)-Ibuprofen

Description:

(-)-Ibuprofen, with the CAS number 51146-57-7, is a nonsteroidal anti-inflammatory drug (NSAID) commonly used for its analgesic, antipyretic, and anti-inflammatory properties. It is characterized by its chiral structure, with the (-) enantiomer being the active form that exhibits therapeutic effects. The molecular formula of ibuprofen is C13H18O2, and it features a propionic acid moiety, which contributes to its ability to inhibit cyclooxygenase (COX) enzymes, thereby reducing the synthesis of prostaglandins involved in pain and inflammation. (-)-Ibuprofen is typically administered orally and is available in various formulations, including tablets, capsules, and suspensions. It is known for its relatively rapid onset of action and is often used to relieve mild to moderate pain, such as headaches, menstrual cramps, and muscle aches. While generally well-tolerated, it can cause gastrointestinal side effects and should be used with caution in individuals with certain health conditions. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion, which are important for determining dosing regimens.

Formula: C₁₃H₁₈O₂

InChI: InChI=1S/C13H18O2/c1-9(2)8-11-4-6-12(7-5-11)10(3)13(14)15/h4-7,9-10H,8H2,1-3H3,(H,14,15)/t10-/m1/s1

InChI key: InChIKey=HEFNNWSXXWATRW-SNVBAGLBSA-N

SMILES: [C@@H](C(O)=O)(C)C1=CC=C(CC(C)C)C=C1

Synonyms:

• (-)-Ibuprofen
• (-)-Ibuprophen
• (-)-α-Methyl-4-(2-methylpropyl)benzeneacetic acid
• (2R)-2-(4-Isobutylphenyl)propanoic acid
• (R)-(-)-Ibuprofen
• (R)-2-(4-Isobutylphenyl)propanoic acid
• (αR)-α-Methyl-4-(2-methylpropyl)benzeneacetic acid
• Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (R)-
• Benzeneacetic acid, α-methyl-4-(2-methylpropyl)-, (αR)-
• R-(-)-p-Isobutylhydratropic acid
• benzeneacetic acid, alpha-methyl-4-(2-methylpropyl)-, (alphaR)-

(R)-(-)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Purity: 96%

Color and Shape: Solid

Molecular weight: 206.2808

Ref: IN-DA00D9RI

(R)-2-(4-Isobutylphenyl)Propanoic Acid

CAS: 51146-57-7

(R)-2-(4-Isobutylphenyl)Propanoic Acid

Purity: 98%

Molecular weight: 206.28g/mol

Ref: 54-OR1008454

(R)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Color and Shape: White To Off-White Solid

Molecular weight: 206.29

Ref: 4Z-I-046

(R)-(-)-Ibuprofen

CAS: 51146-57-7

(R)-(-)-Ibuprofen

Purity: ≥98%

Molecular weight: 206.28g/mol

Ref: 54-BUP15851

(R)-(-)-Ibuprofen

CAS: 51146-57-7

(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation.

Formula: C₁₃H₁₈O₂

Purity: 99.86%

Color and Shape: Solid

Molecular weight: 206.28

Ref: TM-T17309

(R)-(-)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Purity: >98.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 206.29

Ref: 3B-I1222

(R)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Molecular weight: 206.29

Ref: ST-EA-CP-I2043

(R)-(-)-Ibuprofen

Controlled Product

CAS: 51146-57-7

Applications A nonsteroidal anti-inflammatory drug (NSAID); activity resides primarily in the (S)-isomer.
References Busson, M., et al.: J. Int. Med Res., 14, 53 (1986), Meade, E.A., et al.: J. Biol. Chem., 268, 6610 (1993), Davies, N.M., et al.: Clin. Pharmacokinet., 34, 101 (1998),

Formula: C₁₃H₁₈O₂

Color and Shape: White Solid

Molecular weight: 206.28

Ref: TR-I140005

(R)-(-)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Molecular weight: 206.29

Ref: ST-EA-CP-I2062

(R)-(-)-Ibuprofen

CAS: 51146-57-7

Formula: C₁₃H₁₈O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 206.285

Ref: 10-F053833

(R)-(-)-Ibuprofen

CAS: 51146-57-7

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used to treat pain and inflammation. It belongs to the group of fatty acid derivatives, which are drugs that block the production of prostaglandins. Ibuprofen has been shown to have contraceptive effects in humans and experimental models, as well as an effect on human serum lipoproteins. Ibuprofen has also been shown to inhibit the synthesis of prostaglandins in rat liver microsomes and asymmetric synthesis in wastewater treatment. Its pharmacokinetic properties are determined by its absorption rate, distribution volume, and metabolism rate. The kinetic behavior of ibuprofen is affected by matrix effect and the kinetic behavior of ibuprofen is also affected by its pharmacokinetic properties such as isooctane, carcinoma cell lines, etc.

Formula: C₁₃H₁₈O₂

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 206.28 g/mol

Ref: 3D-FI24527