CAS 51230-19-4

(D-ala6)luteinizing hormone releasing*hormone

Description:

(D-Ala^6)Luteinizing Hormone-Releasing Hormone (LHRH) is a synthetic analog of the naturally occurring gonadotropin-releasing hormone (GnRH), which plays a crucial role in regulating the reproductive hormone cascade. This peptide consists of a sequence of amino acids, with the substitution of D-alanine at the sixth position, which enhances its stability and bioactivity compared to the native hormone. The modification helps to resist enzymatic degradation, making it more effective in therapeutic applications. LHRH and its analogs are primarily used in clinical settings for the treatment of hormone-sensitive conditions, such as prostate cancer and endometriosis, by modulating the release of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). The compound is typically administered via injection due to its peptide nature, which limits oral bioavailability. Its pharmacological profile includes the ability to downregulate gonadotropin secretion when used in a continuous manner, a mechanism that is exploited in various hormonal therapies. Overall, (D-Ala^6)LHRH exemplifies the importance of peptide modifications in enhancing therapeutic efficacy.

Formula: C₅₆H₇₇N₁₇O₁₃

Synonyms:

• Luteinizing hormone-releasing hormone, (D-ala(sup 6))-
• (D-Ala(sup 6))-LHRH
• (D-Ala(sup 6))-luteinizing hormone-releasing hormone
• Wy-18186
• (D-Ala6)-LHRH
• Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2

(D-Ala⁶)-LHRH

CAS: 51230-19-4

Bachem ID: 4009745.

Formula: C₅₆H₇₇N₁₇O₁₃

Purity: 98.9%

Color and Shape: White

Molecular weight: 1196.33

Ref: 01-4009745

(D-Ala6)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 acetate salt

CAS: 51230-19-4

Please enquire for more information about (D-Ala6)-LHRH acetate salt Pyr-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-Gly-NH2 acetate salt including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₅₆H₇₇N₁₇O₁₃

Purity: Min. 95%

Molecular weight: 1,196.32 g/mol

Ref: 3D-FA109156

[D-Ala6]-LH-RH

CAS: 51230-19-4

[D-Ala6]-LH-RH, a Luteinizing-hormone-releasing hormone (LHRH) analogue, functions as a gonadotropin-releasing hormone (GnRH) receptor agonist [1].

Formula: C₅₆H₇₇N₁₇O₁₃

Color and Shape: Solid

Molecular weight: 1196.32

Ref: TM-T76351