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CAS 51248-35-2

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DL-Leucine N-carboxy anhydride

Description:
DL-Leucine N-carboxy anhydride (CAS 51248-35-2) is a cyclic derivative of the amino acid leucine, characterized by its anhydride functional group. This compound is typically used in peptide synthesis and as a building block in the preparation of polypeptides. It exhibits a white to off-white crystalline appearance and is soluble in organic solvents, such as dimethylformamide and dimethyl sulfoxide, but has limited solubility in water. The anhydride form allows for the formation of peptide bonds, making it a valuable reagent in organic and medicinal chemistry. Its reactivity is influenced by the presence of the anhydride group, which can undergo hydrolysis or react with nucleophiles, facilitating the incorporation of leucine into larger molecular structures. Safety precautions should be taken when handling this compound, as it may cause irritation to the skin, eyes, and respiratory system. Proper storage conditions include a cool, dry place, away from moisture and incompatible substances.
Formula:C7H11NO3
InChI:InChI=1S/C7H11NO3/c1-4(2)3-5-6(9)11-7(10)8-5/h4-5H,3H2,1-2H3,(H,8,10)
InChI key:InChIKey=JHWZWIVZROVFEM-UHFFFAOYSA-N
SMILES:C(C(C)C)C1NC(=O)OC1=O
Synonyms:
  • Leucine, N-carboxy-, cyclic anhydride
  • 2,5-Oxazolidinedione, 4-(2-methylpropyl)-
  • 4-Isobutyloxazolidine-2,5-dione
  • 2,5-Oxazolidinedione, 4-isobutyl-
  • DL-Leucine N-carboxy anhydride
  • 4-(2-Methylpropyl)-2,5-oxazolidinedione
  • Einecs 257-083-3
  • Isobutyloxazolidine-2,5-dione
  • H-DL-Leu-NCA
  • ILE-NCA
  • See more synonyms
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