CAS 51274-83-0

Tiamenidine hydrochloride

Description:

Tiamenidine hydrochloride is a chemical compound primarily used as an antihypertensive agent. It functions as a centrally acting alpha-2 adrenergic agonist, which means it works by stimulating alpha-2 receptors in the brain, leading to a decrease in sympathetic outflow and a subsequent reduction in blood pressure. The substance is typically presented as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in pharmaceutical formulations. Its chemical structure includes a piperidine ring, contributing to its pharmacological activity. Tiamenidine hydrochloride is known for its relatively mild side effects compared to other antihypertensive medications, making it a suitable option for managing hypertension in certain patient populations. However, like all medications, it should be used under medical supervision due to potential interactions and contraindications. As with any pharmaceutical compound, proper dosage and adherence to prescribed guidelines are essential for safety and efficacy.

Formula: C₈H₁₀ClN₃S·ClH

InChI: InChI=1S/C8H10ClN3S.ClH/c1-5-4-13-7(9)6(5)12-8-10-2-3-11-8;/h4H,2-3H2,1H3,(H2,10,11,12);1H

InChI key: InChIKey=RPZYVGSSBVNVCS-UHFFFAOYSA-N

SMILES: N(C=1C(C)=CSC1Cl)C=2NCCN2.Cl

Synonyms:

• Tiamenidine hydrochloride
• 1H-Imidazol-2-amine, N-(2-chloro-4-methyl-3-thienyl)-4,5-dihydro-, monohydrochloride
• 1H-Imidazol-2-amine, N-(2-chloro-4-methyl-3-thienyl)-4,5-dihydro-, hydrochloride (1:1)
• HOE 440
• 2-[(2-Chloro-4-methyl-3-thienyl)amino]-2-imidazoline hydrochloride

Tiamenidine hydrochloride

CAS: 51274-83-0

Tiamenidine hydrochloride is a centrally-acting alpha1 adrenergic receptor antagonist.

Formula: C₈H₁₁Cl₂N₃S

Color and Shape: Solid

Molecular weight: 252.16

Ref: TM-T69169