CAS 513-10-0

Echothiophate iodide

Description:

Echothiophate iodide is an organophosphate compound primarily used as a medication in the treatment of glaucoma and as a miotic agent to constrict the pupil of the eye. It functions as an irreversible inhibitor of the enzyme acetylcholinesterase, leading to increased levels of acetylcholine at synapses, which enhances cholinergic activity. This compound is characterized by its ability to penetrate biological membranes, allowing it to exert its effects on the nervous system. Echothiophate iodide is typically administered topically in the form of eye drops. Its pharmacological effects can include reduced intraocular pressure and improved drainage of aqueous humor. However, due to its mechanism of action, it can also lead to side effects such as blurred vision, headache, and systemic cholinergic effects if absorbed in significant amounts. Safety precautions are necessary when handling this compound, as it can be toxic in higher doses. Overall, echothiophate iodide exemplifies the dual nature of organophosphates, serving therapeutic purposes while also posing potential risks.

Formula: C₉H₂₃INO₃PS

InChI: InChI=1/C9H23NO3PS.HI/c1-6-12-14(11,13-7-2)15-9-8-10(3,4)5;/h6-9H2,1-5H3;1H/q+1;/p-1

InChI key: InChIKey=OVXQHPWHMXOFRD-UHFFFAOYSA-M

SMILES: P(SCC[N+](C)(C)C)(OCC)(OCC)=O.[I-]

Synonyms:

• (2-Mercaptoethyl)trimethylammonium iodide, O,O-diethyl phosphorothioate
• (2-Mercaptoethyl)trimethylammonium iodide, S-ester with O,O-diethyl phosphorothioate
• 2-(Diethoxyphosphinylthio)Ethyltrimethylammonium Iodide
• 2-[(diethoxyphosphoryl)sulfanyl]-N,N,N-trimethylethanaminium iodide
• 217Mi
• Ammonium, (2-mercaptoethyl)trimethyl-, iodide, S-ester with O,O-diethyl phosphorothioate
• Diethoxyphosphinylthiocholine iodide
• Diethylphosphorylthiocholine iodide
• Echothiopate iodide
• Ecostigmine iodide
• Ecostigmini jodidum
• Ecothiopate iodide
• Ethanaminium, 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-, iodide
• Ethanaminium, 2-[(diethoxyphosphinyl)thio]-N,N,N-trimethyl-, iodide (1:1)
• N-[2-(Diethoxyphosphinylthio)ethyl]trimethylammonium iodide
• Phospholine iodide
• S-(2-Dimethylaminoethyl) O,O-diethylphosphorothioate methiodide
• S-(Diethyl phosphono)thiocholine iodide
• Echodide
• PHOSPHOLINEIODIDE
• Ecostigmine
• ECHOTHIOPHATE
• Ecostigmini Sodidum
• Ecothiopate
• Ecothiophate iodide
• ECOTHIOPHATE
• Iodide, Echothiophate
• 2-[(Diethoxyphosphinyl)thio]ethanaminium
• 2-diethoxyphosphorylsulfanylethyl(trimethyl)azanium iodide

Echothiophate Iodide

CAS: 513-10-0

Applications Echothiophate Iodide is an anticholinesterase drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ashani, Y., et al.: Biochem. Pharm., 30, 2593 (1981)

Formula: C₉H₂₃NO₃PS·I

Color and Shape: Neat

Molecular weight: 383.23

Ref: TR-E325800

Echothiopate iodide

CAS: 513-10-0

Echothiopate iodide is a drug used to treat glaucoma, which is characterized by increased pressure in the eye. It works by inhibiting acetylcholinesterase, an enzyme that breaks down acetylcholine, a neurotransmitter that stimulates the muscles of the iris. The drug also has miotic and cholinergic properties. Echothiopate iodide can cause side effects such as headaches, nausea, vomiting, and diarrhea. These side effects are more frequent in patients with liver or kidney problems.
Echothiopate iodide is administered intravenously. It can be given as a single injection or as multiple injections over time.

Formula: C₉H₂₃NO₃PS·I

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 383.23 g/mol

Ref: 3D-FE10638

Echothiophate-d3 Iodide

Controlled Product

CAS: 513-10-0, 6736-03-4

Applications Echothiophate-d3 Iodide is labelled Echothiophate Iodide (E325800), an anticholinesterase drug.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Ashani, Y., et al.: Biochem. Pharm., 30, 2593 (1981)

Formula: C₉D₃H₂₀NO₃PS·I

Color and Shape: Neat

Molecular weight: 386.245

Ref: TR-E325802

Echothiophate Iodide

CAS: 513-10-0

Echothiophate iodide is an effective long-acting cholinesterase inhibitor for the treatment of glaucoma.

Formula: C₉H₂₃INO₃PS

Color and Shape: Solid

Molecular weight: 383.23

Ref: TM-T31600