CAS 51321-79-0

N-Phosphonacetyl-L-aspartic acid

Description:

N-Phosphonacetyl-L-aspartic acid (CAS 51321-79-0) is a synthetic amino acid derivative that serves as a potent inhibitor of the enzyme aspartate transcarbamylase, which is involved in pyrimidine nucleotide biosynthesis. This compound is characterized by its phosphonate group, which contributes to its biochemical activity and stability. It is typically a white to off-white solid that is soluble in water and exhibits a relatively low molecular weight. The presence of both an amino group and a carboxylic acid group in its structure allows it to participate in various chemical reactions, making it useful in biochemical research and pharmaceutical applications. N-Phosphonacetyl-L-aspartic acid is often studied for its potential therapeutic effects, particularly in the context of cancer treatment and metabolic disorders, due to its ability to modulate metabolic pathways. Additionally, its structural features enable it to mimic natural substrates, enhancing its efficacy as an enzyme inhibitor. Overall, this compound is significant in both academic research and potential clinical applications.

Formula: C₆H₁₀NO₈P

InChI: InChI=1S/C6H10NO8P/c8-4(2-16(13,14)15)7-3(6(11)12)1-5(9)10/h3H,1-2H2,(H,7,8)(H,9,10)(H,11,12)(H2,13,14,15)/t3-/m0/s1

InChI key: InChIKey=ZZKNRXZVGOYGJT-VKHMYHEASA-N

SMILES: [C@H](NC(CP(=O)(O)O)=O)(CC(O)=O)C(O)=O

Synonyms:

• (2S)-2-(2-Phosphonoacetamido)butanedioic acid
• (2S)-2-[(2-Phosphonoacetyl)amino]butanedioic acid
• <span class="text-smallcaps">L</span>-Aspartic acid, N-(2-phosphonoacetyl)-
• <span class="text-smallcaps">L</span>-Aspartic acid, N-(phosphonoacetyl)-
• Acide sparfosique
• Acide sparfosique [INN-French]
• Acido sparfosico
• Acido sparfosico [INN-Spanish]
• Acidum sparfosicum
• Acidum sparfosicum [INN-Latin]
• L-Aspartic acid, N-(phosphonoacetyl)-
• N-(2-Phosphonoacetyl)-<span class="text-smallcaps">L</span>-aspartic acid
• N-(Phosphonacetyl)-L-aspartic acid
• N-(Phosphonoacetyl)-<span class="text-smallcaps">L</span>-aspartic acid
• N-(Phosphonoacetyl)-L-aspartic acid
• N-(Phosphonoacetyl)-asparaginsaeure
• N-(phosphonoacetyl)aspartic acid
• N-Phosphonacetyl-<span class="text-smallcaps">L</span>-aspartic acid
• N-Phosphonacetyl-L-aspartate
• Nci 224131
• Nsc 224131
• Pala
• Phosphonoacetyl-<span class="text-smallcaps">L</span>-aspartic acid
• Sparfosic Acid
• Sparfosic Acid [INN]
• Unii-78Qvz7Rg8L
• tetrasodium (2S)-2-[(phosphonatoacetyl)amino]butanedioate
• L-Aspartic acid, N-(2-phosphonoacetyl)-

Sparfosic Acid

CAS: 51321-79-0

Sparfosic Acid

Purity: ≥98%

Molecular weight: 255.12g/mol

Ref: 54-BUP00996

Sparfosic Acid

CAS: 51321-79-0

Sparfosic Acid (Acide sparfosique) is an aspartate carbamoyltransferase inhibitor with antitumor activity and can be used to study advanced renal cell carcinoma

Formula: C₆H₁₀NO₈P

Purity: 98.89%

Color and Shape: Solid

Molecular weight: 255.12

Ref: TM-T24818