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CAS 51322-75-9

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Tizanidine

Description:
Tizanidine is a muscle relaxant primarily used to manage spasticity associated with conditions such as multiple sclerosis and spinal cord injuries. It functions as an alpha-2 adrenergic agonist, which means it works by inhibiting the release of excitatory neurotransmitters, leading to reduced muscle tone and spasm. The chemical formula for Tizanidine is C12H16ClN5O, and it has a molecular weight of approximately 248.74 g/mol. Tizanidine is typically administered in oral form and is known for its relatively rapid onset of action, although it may cause sedation and hypotension as side effects. Its pharmacokinetics involve hepatic metabolism, primarily through the cytochrome P450 system, and it has a relatively short half-life, necessitating multiple doses throughout the day for sustained effect. Due to its sedative properties, caution is advised when combining Tizanidine with other central nervous system depressants. Overall, Tizanidine is an effective treatment option for muscle spasticity, but it requires careful management to mitigate potential side effects.
Formula:C9H8ClN5S
InChI:InChI=1S/C9H8ClN5S/c10-5-1-2-6-8(15-16-14-6)7(5)13-9-11-3-4-12-9/h1-2H,3-4H2,(H2,11,12,13)
InChI key:InChIKey=XFYDIVBRZNQMJC-UHFFFAOYSA-N
SMILES:N(C=1C=2C(C=CC1Cl)=NSN2)C=3NCCN3
Synonyms:
  • (5-Chloro-benzo[1,2,5]thiadiazol-4-yl)-(4,5-dihydro-1H-imidazol-2-yl)-amine
  • 2,1,3-Benzothiadiazol-4-amine, 5-chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-
  • Tizanidine
  • 5-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-2,1,3-benzothiadiazol-4-amine
  • Tizalud
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Found 5 products.