CAS 51379-07-8

Bis-(4-methylumbelliferyl)-phosphate

Description:

Bis-(4-methylumbelliferyl)-phosphate, with the CAS number 51379-07-8, is a synthetic organic compound commonly used as a substrate in biochemical assays, particularly in enzyme activity studies. This compound features two 4-methylumbelliferyl groups linked by a phosphate moiety, which makes it a fluorogenic substrate. Upon enzymatic hydrolysis, it releases 4-methylumbelliferone, a fluorescent product that can be detected and quantified, allowing for sensitive measurements of enzyme activity. The compound is typically soluble in organic solvents and exhibits a characteristic fluorescence under UV light, making it useful in various applications, including molecular biology and biochemistry. Its stability and specificity for certain phosphatases enhance its utility in research settings. Additionally, safety precautions should be observed when handling this compound, as with many chemical substances, to mitigate any potential health risks.

Formula: C₂₀H₁₅O₈P

InChI: InChI=1/C20H15O8P/c1-11-7-19(21)25-17-9-13(3-5-15(11)17)27-29(23,24)28-14-4-6-16-12(2)8-20(22)26-18(16)10-14/h3-10H,1-2H3,(H,23,24)

InChI key: InChIKey=FEGSOIMPQDYXJD-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC(OP(OC=3C=C4C(=CC3)C(C)=CC(=O)O4)(=O)O)=CC2)OC(=O)C1

Synonyms:

• 2H-1-Benzopyran-2-one, 7,7'-(phosphinicobis(oxy))bis(4-methyl)-
• 7,7'-(Phosphinicobis(oxy))bis(4-methyl-2H-1-benzopyran-2-one)
• bis(4-methyl-2-oxo-2H-chromen-7-yl) hydrogen phosphate
• Bis-(4-methylumbelliferyl)phosphate
• Bis(4-methylumbelliferyl) phosphate
• BIS(4-METHYLUMBELLIFERYL)PHOSPHATE ISO 9001：2015 REACH
• Bis-(4-methylumbelliferyl)phosphate(freeacid)
• Phosphoric acid hydrogen bis(4-methyl-2-oxo-2H-1-benzopyran-7-yl) ester
• 2H-1-Benzopyran-2-one,7,7'-[phosphinicobis(oxy)]bis[4-methyl- (9CI)
• BIS-MUP
• bis(4-Methyl-2-oxo-chromen-7-yl) hydrogen phosphate
• BIS(MU)-PHOS

bis-(4-Methylumbelliferyl)phosphate

CAS: 51379-07-8

Formula: C₂₀H₁₅O₈P

Molecular weight: 414.30

Ref: 7W-GC2017

Bis(4-methylumbelliferyl) phosphate

CAS: 51379-07-8

Bis(4-methylumbelliferyl) phosphate

Formula: C₂₀H₁₅O₈P

Purity: Tlc: single spot; free (Typical Value in Batch COA)

Color and Shape: slightly off-white powder

Molecular weight: 414.30g/mol

Ref: 54-BIM2048

Bis-(4-methylumbelliferyl)phosphate

CAS: 51379-07-8

Bis-(4-methylumbelliferyl)phosphate, or bis-4MU-phopshate, is a fluorogenic substrate used to study phosphatase activity, particularly in enzyme-linked immunosorbent assays (ELISAs).

Formula: C₂₀H₁₅O₈P

Purity: Min. 95 Area-%

Color and Shape: White Powder

Molecular weight: 414.3 g/mol

Ref: 3D-EB15696

Bis(4-methylumbelliferyl)phosphate

CAS: 51379-07-8

Bis(4-methylumbelliferyl)phosphate is a fluorescent probe that can be used for the diagnosis of β-glucosidase. It has a phosphate group and can be used to study phosphodiesterases and phosphodiesters. Bis(4-methylumbelliferyl)phosphate is also a liposomal probe that can be used in kinetic studies. This compound has been shown to inhibit β-glucosidase, which is an enzyme found in human saliva and pancreatic juice, at high concentrations. The inhibition of this enzyme leads to the accumulation of glucose and galactose in the blood, which can lead to diabetes mellitus or cancer.

Formula: C₂₀H₁₅O₈P

Molecular weight: 414.31 g/mol

Ref: 3D-B-3500