CAS 51388-20-6

Benzenamine, 4-(phenylmethoxy)-, hydrochloride (1:1)

Description:

Benzenamine, 4-(phenylmethoxy)-, hydrochloride (1:1), also known as 4-(benzyloxy)aniline hydrochloride, is an organic compound characterized by its amine and ether functional groups. It features a benzene ring substituted with a phenylmethoxy group and an amino group at the para position. The hydrochloride form indicates that the compound is a salt, which enhances its solubility in water compared to its free base form. This compound typically appears as a white to off-white crystalline solid. It is often used in organic synthesis and may serve as an intermediate in the production of dyes, pharmaceuticals, or other chemical compounds. The presence of the amino group allows for potential reactivity in various chemical reactions, including nucleophilic substitutions and coupling reactions. Safety data should be consulted, as with any chemical, to understand its handling, storage, and potential hazards. Overall, benzenamine derivatives are significant in medicinal chemistry and materials science due to their diverse applications.

Formula: C₁₃H₁₃NO·ClH

InChI: InChI=1S/C13H13NO.ClH/c14-12-6-8-13(9-7-12)15-10-11-4-2-1-3-5-11;/h1-9H,10,14H2;1H

InChI key: InChIKey=KQBDLOVXZHOAJI-UHFFFAOYSA-N

SMILES: O(CC1=CC=CC=C1)C2=CC=C(N)C=C2.Cl

Synonyms:

• 4-(Benzyloxy)aniline hydrochloride
• 4-(Phenylmethoxy)aniline hydrochloride
• 4-Aminodiphenyl ether hydrochloride
• 4-Benzyloxyaniline hydrochloric acid salt
• 4-Benzyloxyphenylamine hydrochloride
• 4-[(Phenylmethyl)oxy]aniline hydrochloride
• Benzenamine, 4-(phenylmethoxy)-, hydrochloride
• Benzenamine, 4-(phenylmethoxy)-, hydrochloride (1:1)
• p-(Benzyloxy)aniline hydrochloride

4-Benzyloxyaniline hydrochloride, 98%

CAS: 51388-20-6

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₃H₁₄ClNO

Purity: 98%

Color and Shape: Cream to brown or pale grey to pale pink to pink, Crystals or powder or crystalline powder

Molecular weight: 235.71

Ref: 02-A16856

4-Benzyloxyaniline, HCl

CAS: 51388-20-6

Formula: C₁₃H₁₄ClNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.7094

Ref: IN-DA003600

4-Benzyloxyaniline hydrochloride

CAS: 51388-20-6

Formula: C₁₃H₁₃NOHCl

Molecular weight: 235.72

Ref: 7W-GK8235

4-(Benzyloxy)aniline hydrochloride

CAS: 51388-20-6

4-(Benzyloxy)aniline hydrochloride

Formula: C₁₃H₁₃NO·ClH

Purity: ≥95%

Color and Shape: faint brown solid

Molecular weight: 235.71g/mol

Ref: 54-OR8024

4-Benzyloxyaniline hydrochloride

CAS: 51388-20-6

4-Benzyloxyaniline hydrochloride (4BOAH) is a pro-apoptotic agent that induces cell death by binding to the estrogen receptor. It binds to the cytoplasmic region of the estrogen receptor, which prevents the estrogen receptor from binding to its target DNA sequence. This leads to apoptosis and cell death. 4BOAH has been shown to be an effective inhibitor of breast cancer in animal models and also shows anti-estrogen activity in human liver cells. 4BOAH is a reactive compound with a molecular weight of 239.46 g/mol, an empirical formula C9H11NO2Cl, and structural formula H-C-N=C=O. 4BOAH forms hydrogen bonds with other molecules because it has a lone pair of electrons on the nitrogen atom and can form covalent bonds with amines due to its electron withdrawing properties. The structure of 4BOAH is shown below:

Formula: C₁₃H₁₃NO·HCl

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 235.71 g/mol

Ref: 3D-FB52481

4-(Benzyloxy)aniline hydrochloride

CAS: 51388-20-6

Formula: C₁₃H₁₄ClNO

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.71

Ref: 10-F078009

4-(Benzyloxy)aniline Hydrochloride

Controlled Product

CAS: 51388-20-6

Applications 4-(Benzyloxy)aniline Hydrochloride is used as a reagent in the synthesis of a series of amino acid derivatives as novel chromogenic enzyme substrates for the detection of aminopeptidase activity in clinically important microorganisms.
References Cellier, M., et al.: Bioorg. Med. Chem., 22, 5249 (2014)

Formula: C₁₆H₂₀FN₃O₂S

Color and Shape: Neat

Molecular weight: 337.412

Ref: TR-B285490