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CAS 51481-65-3

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Mezlocillin

Description:
Mezlocillin is a semi-synthetic penicillin antibiotic that belongs to the class of beta-lactam antibiotics. It is primarily used to treat infections caused by susceptible bacteria, particularly those that are gram-negative. Mezlocillin exhibits a broad spectrum of antibacterial activity, making it effective against various pathogens, including Pseudomonas aeruginosa. The chemical structure of mezlocillin includes a beta-lactam ring, which is essential for its antibacterial action, as it inhibits bacterial cell wall synthesis. This compound is typically administered via injection due to its instability in acidic environments, which limits its oral bioavailability. Mezlocillin is often used in clinical settings for treating serious infections, particularly in immunocompromised patients or those with complicated infections. As with other antibiotics, it is important to use mezlocillin judiciously to prevent the development of antibiotic resistance. Common side effects may include allergic reactions, gastrointestinal disturbances, and potential interactions with other medications.
Formula:C21H25N5O8S2
InChI:InChI=1/C16H26N2O5S/c1-16(2)8-10(16)13(19)18-12(15(22)23)6-4-3-5-7-24-9-11(17)14(20)21/h6,10-11H,3-5,7-9,17H2,1-2H3,(H,18,19)(H,20,21)(H,22,23)/b12-6-/t10-,11+/m0/s1
InChI key:InChIKey=YPBATNHYBCGSSN-VWPFQQQWSA-N
SMILES:N(C([C@H](NC(=O)N1C(=O)N(S(C)(=O)=O)CC1)C2=CC=CC=C2)=O)[C@H]3[C@@]4(N([C@@H](C(O)=O)C(C)(C)S4)C3=O)[H]
Synonyms:
  • (2S,5R,6R)-3,3-Dimethyl-6-[[(2R)-2-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]-2-phenylacetyl]amino]-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(2R)-2-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]-2-phenylacetyl]amino]-7-oxo-, (2S,5R,6R)-
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, [2S-[2α,5α,6β(S*)]]-
  • BAY-f 1353
  • Mezlocillin
  • Mezlocillina
  • Mezlocilline
  • 3,3-dimethyl-6-{[({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)(phenyl)acetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • (2S,5R,6R)-3,3-dimethyl-6-{[(2R)-2-({[3-(methylsulfonyl)-2-oxoimidazolidin-1-yl]carbonyl}amino)-2-phenylacetyl]amino}-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid
  • 4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 3,3-dimethyl-6-[[(2R)-[[[3-(methylsulfonyl)-2-oxo-1-imidazolidinyl]carbonyl]amino]phenylacetyl]amino]-7-oxo-, (2S,5R,6R)-
  • See more synonyms
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