CAS 51529-34-1

H-Gly-Met-Gly-OH

Description:

The chemical substance known as H-Gly-Met-Gly-OH, with the CAS number 51529-34-1, is a peptide composed of three amino acids: glycine (Gly), methionine (Met), and another glycine (Gly). This peptide is characterized by its relatively simple structure, which includes an N-terminal histidine (H) and a C-terminal hydroxyl group (OH). It is typically classified as a dipeptide or tripeptide, depending on the context of its use. The presence of methionine introduces a sulfur atom, which can participate in various biochemical processes, including redox reactions. Peptides like H-Gly-Met-Gly-OH are often studied for their potential biological activities, including antioxidant properties and roles in cellular signaling. They may also serve as building blocks for more complex biomolecules or as therapeutic agents in drug development. The stability, solubility, and reactivity of this peptide can be influenced by factors such as pH and temperature, making it important to consider these conditions in experimental applications.

Formula: C₉H₁₇N₃O₄S

InChI: InChI=1/C9H17N3O4S/c1-17-3-2-6(12-7(13)4-10)9(16)11-5-8(14)15/h6H,2-5,10H2,1H3,(H,11,16)(H,12,13)(H,14,15)/t6-/m0/s1

SMILES: CSCC[C@@H](C(=NCC(=O)O)O)N=C(CN)O

Synonyms:

• Glycine, N-(N-glycyl-L-methionyl)-
• Glycylmethionylglycine
• 4-(Glycylamino)-6-(Methylsulfanyl)-3-Oxonorleucine
• {[N-(ammonioacetyl)-L-methionyl]amino}acetate

H-Gly-Met-Gly-OH

CAS: 51529-34-1

Formula: C₉H₁₇N₃O₄S

Molecular weight: 263.3140

Ref: IN-DA00DCAX

H-Gly-Met-Gly-OH

CAS: 51529-34-1

H-Gly-Met-Gly-OH is an amide containing a sulfoxide group. It is synthesized from the amino acid glycine and the tripeptide Met-Gly-Gly. The synthesis of HMG was first reported by Sato in 1907, although it was not used as a drug until 1983. This drug has potential antitumor activity and inhibits the growth of certain tumor cells. HMG is metabolized by peptidases, which hydrolyze the peptide bond between glycine and Met-Gly-Gly. Hydrolysis of HMG yields glyoxylic acid (H2O2) and the amino acids glycine and methanol. HMG also inhibits the uptake of glucose into cells, which may be related to its antitumor effect. X-ray diffraction studies have shown that HMG has a carboxylate group at C6 that binds to three oxygen atoms, which are present in two

Formula: C₉H₁₇N₃O₄S

Purity: Min. 95%

Molecular weight: 263.32 g/mol

Ref: 3D-FG109044