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CAS 51543-39-6

:

(+)-Flurbiprofen

Description:
(+)-Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. This compound is a chiral molecule, existing in two enantiomeric forms, with the (+) enantiomer being the active form. (+)-Flurbiprofen is typically administered in oral form and is known for its effectiveness in treating conditions such as arthritis, dysmenorrhea, and other inflammatory disorders. The substance is generally well-absorbed in the gastrointestinal tract, with its pharmacokinetics influenced by factors such as dosage and individual metabolism. Common side effects may include gastrointestinal discomfort, dizziness, and potential cardiovascular risks, particularly with long-term use. As with all NSAIDs, it is essential to use (+)-Flurbiprofen under medical supervision to mitigate risks and ensure appropriate therapeutic outcomes.
Formula:C15H13FO2
InChI:InChI=1/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m0/s1
InChI key:InChIKey=SYTBZMRGLBWNTM-JTQLQIEISA-N
SMILES:FC1=C(C=CC([C@@H](C(O)=O)C)=C1)C2=CC=CC=C2
Synonyms:
  • (+)-(S)-Flurbiprofen
  • (+)-Flurbiprofen
  • (2S)-2-(2-Fluoro-1,1′-biphenyl-4-yl)propanoic acid
  • (2S)-2-(2-Fluoro-4-biphenyl)propanoic acid
  • (2S)-2-(2-fluorobiphenyl-4-yl)propanoic acid
  • (S)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)propanoic acid
  • (S)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)propanoicacid
  • (S)-2-(2-Fluorobiphenyl-4-yl)propanoic acid
  • (S)-2-Fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic acid
  • (S)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
  • See more synonyms
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