CAS 51543-39-6

(+)-Flurbiprofen

Description:

(+)-Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase (COX) enzymes, which play a crucial role in the synthesis of prostaglandins, mediators of inflammation and pain. This compound is a chiral molecule, existing in two enantiomeric forms, with the (+) enantiomer being the active form. (+)-Flurbiprofen is typically administered in oral form and is known for its effectiveness in treating conditions such as arthritis, dysmenorrhea, and other inflammatory disorders. The substance is generally well-absorbed in the gastrointestinal tract, with its pharmacokinetics influenced by factors such as dosage and individual metabolism. Common side effects may include gastrointestinal discomfort, dizziness, and potential cardiovascular risks, particularly with long-term use. As with all NSAIDs, it is essential to use (+)-Flurbiprofen under medical supervision to mitigate risks and ensure appropriate therapeutic outcomes.

Formula: C₁₅H₁₃FO₂

InChI: InChI=1/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m0/s1

InChI key: InChIKey=SYTBZMRGLBWNTM-JTQLQIEISA-N

SMILES: FC1=C(C=CC([C@@H](C(O)=O)C)=C1)C2=CC=CC=C2

Synonyms:

• (+)-(S)-Flurbiprofen
• (+)-Flurbiprofen
• (2S)-2-(2-Fluoro-1,1′-biphenyl-4-yl)propanoic acid
• (2S)-2-(2-Fluoro-4-biphenyl)propanoic acid
• (2S)-2-(2-fluorobiphenyl-4-yl)propanoic acid
• (S)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)propanoic acid
• (S)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)propanoicacid
• (S)-2-(2-Fluorobiphenyl-4-yl)propanoic acid
• (S)-2-Fluoro-alpha-methyl(1,1'-biphenyl)-4-acetic acid
• (S)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
• (αS)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid
• 2-(2-Fluorobiphenyl-4-Yl)Propanoic Acid
• Dexflurbiprofen
• Esflurbiprofene [French]
• Esflurbiprofeno [Spanish]
• Esflurbiprofenum [Latin]
• Unii-J5Zzk9P7Mx
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (S)-
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (αS)-
• d-Flurbiprofen
• (S)-(+)-2-Fluoro-α-methyl-4-biphenylacetic acid
• (S)-Flurbiprofen USP/EP/BP
• (S)-2-(2-Fluoro-1,1'-biphenyl-4-yl)propionic acid
• (S)-(+)-2-Fluoro-alpha-methyl-4-biphenylacetic acid (Flurbiprofe
• Esflurbiprofen
• Flurbiprofen (S)-Isomer
• (S)-(+)-2-FLUORO-ALPHA-METHYL-4-BIPHENYLACETIC ACID (FLURBIPROFEN)
• BTS-24332,SFPP,TT-063,Esflurbiprofen
• (S)-2-Flurbiprofen
• [1,1'-Biphenyl]-4-aceticacid, 2-fluoro-a-methyl-,(aS)-
• (S)-3-Fluoro-α-methyl-4-phenylbenzeneacetic acid

(S)-2-(2-Fluoro-[1,1'-biphenyl]-4-yl)propanoic acid

CAS: 51543-39-6

Formula: C₁₅H₁₃FO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.2609

Ref: IN-DA006VM0

(S)-(+)-2-Fluoro-α-methyl-4-biphenylacetic acid (Flurbiprofen)

CAS: 51543-39-6

Ref: 7W-GP2700

(S)-Flurbiprofen

CAS: 51543-39-6

(S)-Flurbiprofen

Purity: ≥98%

Molecular weight: 244.26g/mol

Ref: 54-BUP16414

(S)-Flurbiprofen

CAS: 51543-39-6

Formula: C₁₅H₁₃FO₂

Color and Shape: White To Off-White Solid

Molecular weight: 244.27

Ref: 4Z-F-0814

Esflurbiprofen

Controlled Product

CAS: 51543-39-6

Formula: C₁₅H₁₃FO₂

Color and Shape: Neat

Molecular weight: 244.26

Ref: 86-MM3707.00

(S)-Flurbiprofen

CAS: 51543-39-6

Esflurbiprofen is an inhibitor of COX-1 and COX-2.

Formula: C₁₅H₁₃FO₂

Purity: 99.99%

Color and Shape: White To Yellowish Crystalline Powder

Molecular weight: 244.26

Ref: TM-T5843L

(S)-Flurbiprofen

Controlled Product

CAS: 51543-39-6

Applications (S)-2-Flurbiprofen is the S-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chalmers, et al.: Ann. Rheum. Dis., 31, 319 (1972), Nishizawa, et al.: Thromb. Res., 3, 577 (1973)

Formula: C₁₅H₁₃FO₂

Color and Shape: White

Molecular weight: 244.26

Ref: TR-F598735

Flurbiprofen (S)-Isomer

CAS: 51543-39-6

Formula: C₁₅H₁₃FO₂

Molecular weight: 244.26

Ref: ST-EA-CP-F21009

(S)-2-(2-Fluoro-[1,1′-biphenyl]-4-yl)propanoic acid

CAS: 51543-39-6

Formula: C₁₅H₁₃FO₂

Purity: 98%

Molecular weight: 244.265

Ref: 10-F319954