CAS 51543-40-9

(-)-Flurbiprofen

Description:

(-)-Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its chiral nature, existing as a single enantiomer, which contributes to its pharmacological activity. The compound is typically presented as a white to off-white crystalline powder and is soluble in organic solvents like ethanol and methanol, but has limited solubility in water. Its mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, leading to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. (-)-Flurbiprofen is often utilized in the treatment of conditions such as arthritis, dental pain, and other inflammatory disorders. Additionally, it has been studied for its potential role in managing certain types of cancer due to its ability to modulate inflammatory pathways. As with other NSAIDs, it may have side effects, including gastrointestinal discomfort and cardiovascular risks, necessitating careful consideration of its use in patients with specific health conditions.

Formula: C₁₅H₁₃FO₂

InChI: InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1

InChI key: InChIKey=SYTBZMRGLBWNTM-SNVBAGLBSA-N

SMILES: FC1=C(C=CC([C@H](C(O)=O)C)=C1)C2=CC=CC=C2

Synonyms:

• (-)-(R)-Flurbiprofen
• (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
• (2R)-2-(3-Fluoro-4-phenylphenyl)propanoic acid
• (R)-(-)-2-(2-Fluorobiphenyl-4-yl)propionic acid
• (R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
• (R)-2-Flurbiprofen
• (αR)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid
• 1,4-Bis(1,1,1,2,3,3,3-Heptafluoropropan-2-Yl)Benzene
• E 7869
• Flurbiprofen
• Flurizan
• Mpc 7869
• Tarenflurbil
• [1,1'-biphenyl]-4-acetic acid, 2-fluoro-alpha-methyl-, (alphaR)-
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (R)-
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (αR)-

(R)-()-2-Fluoro-α-methyl-4-biphenylacetic acid

CAS: 51543-40-9

Formula: C₁₅H₁₃FO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 244.2609

Ref: IN-DA003C3U

(R)-Flurbiprofen

CAS: 51543-40-9

Formula: C₁₅H₁₃FO₂

Molecular weight: 244.27

Ref: 4Z-F-0815

Tarenflurbil

CAS: 51543-40-9

Tarenflurbil

Purity: ≥98%

Molecular weight: 244.26g/mol

Ref: 54-BUP17525

(R)-(-)-2-Fluoro-α-methyl-4-biphenylacetic acid

CAS: 51543-40-9

Formula: C₁₅H₁₃FO₂

Purity: ≥ 95%

Color and Shape: White to off-white crystalline powder or solid

Molecular weight: 244.26

Ref: 7W-GP4315

Tarenflurbil

CAS: 51543-40-9

Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.

Formula: C₁₅H₁₃FO₂

Purity: 98% - 99.9%

Color and Shape: Solid

Molecular weight: 244.26

Ref: TM-T5843

Flurbiprofen (R)-Isomer

CAS: 51543-40-9

Formula: C₁₅H₁₃FO₂

Molecular weight: 244.26

Ref: ST-EA-CP-F21010

(R)-Flurbiprofen

Controlled Product

CAS: 51543-40-9

Applications (R)-2-Flurbiprofen is the R-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Chalmers, et al.: Ann. Rheum. Dis., 31, 319 (1972), Nishizawa, et al.: Thromb. Res., 3, 577 (1973)

Formula: C₁₅H₁₃FO₂

Color and Shape: Neat

Molecular weight: 244.26

Ref: TR-F598730

R-(-)-Flurbiprofen

CAS: 51543-40-9

Formula: C₁₅H₁₃FO₂

Purity: 95.0%

Color and Shape: No data available.

Molecular weight: 244.265

Ref: 10-F245811

(R)-2-Flurbiprofen-d3

Controlled Product

CAS: 51543-40-9

Formula: C₁₅D₃H₁₀FO₂

Color and Shape: Neat

Molecular weight: 247.279

Ref: TR-F598732