CAS 51543-40-9: (-)-Flurbiprofen

Description: (-)-Flurbiprofen is a nonsteroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its chiral nature, existing as a single enantiomer, which contributes to its pharmacological activity. The compound is typically presented as a white to off-white crystalline powder and is soluble in organic solvents like ethanol and methanol, but has limited solubility in water. Its mechanism of action involves the inhibition of cyclooxygenase (COX) enzymes, leading to a decrease in the synthesis of prostaglandins, which are mediators of inflammation and pain. (-)-Flurbiprofen is often utilized in the treatment of conditions such as arthritis, dental pain, and other inflammatory disorders. Additionally, it has been studied for its potential role in managing certain types of cancer due to its ability to modulate inflammatory pathways. As with other NSAIDs, it may have side effects, including gastrointestinal discomfort and cardiovascular risks, necessitating careful consideration of its use in patients with specific health conditions.

Formula: C₁₅H₁₃FO₂

InChI: InChI=1S/C15H13FO2/c1-10(15(17)18)12-7-8-13(14(16)9-12)11-5-3-2-4-6-11/h2-10H,1H3,(H,17,18)/t10-/m1/s1

InChI key: InChIKey=SYTBZMRGLBWNTM-SNVBAGLBSA-N

SMILES: O=C(O)C(C=1C=CC(=C(F)C1)C=2C=CC=CC2)C

Synonyms:

• (-)-(R)-Flurbiprofen
• (2R)-2-(2-fluorobiphenyl-4-yl)propanoic acid
• (2R)-2-(3-Fluoro-4-phenylphenyl)propanoic acid
• (R)-(-)-2-(2-Fluorobiphenyl-4-yl)propionic acid
• (R)-(-)-2-Fluoro-alpha-methyl-4-biphenylacetic acid
• (R)-2-Flurbiprofen
• (αR)-2-Fluoro-α-methyl[1,1′-biphenyl]-4-acetic acid
• 1,4-Bis(1,1,1,2,3,3,3-Heptafluoropropan-2-Yl)Benzene
• E 7869
• Flurbiprofen
• Flurizan
• Mpc 7869
• Tarenflurbil
• [1,1'-biphenyl]-4-acetic acid, 2-fluoro-alpha-methyl-, (alphaR)-
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (R)-
• [1,1′-Biphenyl]-4-acetic acid, 2-fluoro-α-methyl-, (αR)-
• l-Flurbiprofen

(R)-()-2-Fluoro-α-methyl-4-biphenylacetic acid

CAS: 51543-40-9

• Formula: C₁₅H₁₃FO₂
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 244.2609

(R)-Flurbiprofen

CAS: 51543-40-9

• Formula: C₁₅H₁₃FO₂
• Molecular weight: 244.27

Tarenflurbil

CAS: 51543-40-9

• Purity: 99.9%
• Molecular weight: 244.26g/mol

(R)-(-)-Flurbiprofen, 97%

CAS: 51543-40-9

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₁₅H₁₃FO₂
• Purity: 97%
• Color and Shape: White to off-white, Crystalline powder
• Molecular weight: 244.27

Tarenflurbil

CAS: 51543-40-9

Tarenflurbil, the R-enantiomer of flurbiprofen, lacks COX inhibition and was tested for Alzheimer's treatment.

• Formula: C₁₅H₁₃FO₂
• Purity: 100% - 98%
• Color and Shape: Solid
• Molecular weight: 244.26

(R)-(-)-2-Fluoro-α-methyl-4-biphenylacetic acid

CAS: 51543-40-9

• Formula: C₁₅H₁₃FO₂
• Purity: ≥ 95%
• Color and Shape: White to off-white crystalline powder or solid
• Molecular weight: 244.26

R-(-)-Flurbiprofen

CAS: 51543-40-9

• Purity: 95.0%
• Color and Shape: Liquid, No data available.
• Molecular weight: 244.26499938964844

(R)-Flurbiprofen

CAS: 51543-40-9

Applications (R)-2-Flurbiprofen is the R-isomer of Flurbiprofen (F598700), an anti-inflammatory used as an analgesic. Not …

• Formula: C₁₅H₁₃FO₂
• Color and Shape: Neat
• Molecular weight: 244.26

(R)-2-Flurbiprofen-d3

CAS: 51543-40-9

• Formula: C₁₅D₃H₁₀FO₂
• Color and Shape: Neat
• Molecular weight: 247.279

(R)-2-Flurbiprofen

CAS: 51543-40-9

(R)-2-Flurbiprofen is a nonsteroidal anti-inflammatory drug that binds to the dna of the cyclooxygenase enzyme, …

• Formula: C₁₅H₁₃O₂F
• Purity: Min. 95%
• Color and Shape: White Powder
• Molecular weight: 244.26 g/mol