![Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fcas-image%2Fthumb-webp%2F432972-adenosine-2-deoxy-3-o-11-dimethylethyl-dimethylsilyl.webp&w=3840&q=75)
CAS 51549-31-6
:Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
Description:
Adenosine, 2'-deoxy-3'-O-[(1,1-dimethylethyl)dimethylsilyl]- is a modified nucleoside derivative of adenosine, which is a fundamental building block of nucleic acids. This compound features a deoxyribose sugar, indicating the absence of an oxygen atom at the 2' position compared to ribonucleosides. The presence of a silyl protecting group, specifically a tert-butyldimethylsilyl (TBDMS) group at the 3' position, enhances its stability and solubility, making it useful in synthetic organic chemistry, particularly in the synthesis of oligonucleotides. The silyl group can be removed under specific conditions, allowing for further functionalization or incorporation into larger molecular structures. This compound is typically used in biochemical research and applications involving nucleic acid synthesis, where protecting groups are essential for selective reactions. Its CAS number, 51549-31-6, uniquely identifies this chemical substance in databases, facilitating its recognition and study in scientific literature.
Formula:C16H27N5O3Si
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Found 5 products.
3’-O-(t-Butyldimethylsilyl)-2’-deoxyadenosine
CAS:Formula:C16H27N5O3SiPurity:98%Molecular weight:365.50283'-O-(tert-butyldiMethylsilyl)-2'-deoxyadenosine
CAS:<p>3'-O-(tert-butyldiMethylsilyl)-2'-deoxyadenosine</p>Purity:98%3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine
CAS:3'-O-(t-Butyldimethylsilyl)-2'-deoxyadenosine is a Nucleoside Derivative - Protected nucleoside with NH2/OH group open.Formula:C16H27N5O3SiColor and Shape:SolidMolecular weight:365.53’-O-tert-Butyldimethylsilyl-2’-deoxyadenosine
CAS:<p>3’-O-tert-Butyldimethylsilyl-2’-deoxyadenosine is a nucleoside that is used as an antiviral and anticancer drug. It inhibits viral RNA synthesis by acting as a competitive inhibitor of the enzyme ribonucleotide reductase, which converts ribonucleotides to deoxyribonucleotides. 3′-O-tert-Butyldimethylsilyl-2’-deoxyadenosine has been shown to inhibit cancer cells in vitro and in vivo. This compound also has antiangiogenic effects and may inhibit tumor cell proliferation by targeting the Ras/Raf/MEK/ERK pathway.</p>Purity:Min. 95%
