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CAS 51549-36-1

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Cytidine,N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI)

Description:
Cytidine, N-benzoyl-2'-deoxy-5'-O-[(1,1-dimethylethyl)dimethylsilyl]- (9CI), with the CAS number 51549-36-1, is a modified nucleoside derivative of cytidine. This compound features a benzoyl group at the N position, which enhances its stability and solubility, making it useful in various biochemical applications. The presence of a 5'-O-silyl group, specifically a tert-butyldimethylsilyl (TBDMS) moiety, provides protection against hydrolysis, allowing for selective reactions in synthetic pathways. The 2'-deoxy configuration indicates that it lacks a hydroxyl group at the 2' position, which is characteristic of DNA nucleosides, thus influencing its biological activity and interactions. This compound is often utilized in nucleic acid chemistry, particularly in the synthesis of oligonucleotides and other nucleic acid analogs. Its structural modifications contribute to its utility in research and potential therapeutic applications, particularly in the development of antiviral and anticancer agents. As with many chemical substances, handling should be conducted with care, following appropriate safety protocols.
Formula:C22H31N3O5Si
Synonyms:
  • N4-Benzoyl-5'-O-Tert-Butyldimethylsilyl-2'-Deoxycytidine
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