CAS 51568-18-4
:Succinylacetone
Description:
Succinylacetone is an organic compound characterized by its structure, which includes a five-carbon chain with two carbonyl groups. It is a colorless to pale yellow solid that is soluble in organic solvents but has limited solubility in water. Succinylacetone is known for its role as a biomarker in certain metabolic disorders, particularly in the diagnosis of tyrosinemia type I, where it accumulates due to the deficiency of specific enzymes involved in the breakdown of tyrosine. The compound exhibits both ketone and carboxylic acid functional groups, contributing to its reactivity and potential interactions with biological systems. Additionally, succinylacetone can chelate metal ions, which may influence its biological activity and toxicity. Its synthesis typically involves the condensation of acetic acid derivatives and succinic acid, and it can be analyzed using techniques such as mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy. Overall, succinylacetone serves as an important compound in both clinical diagnostics and biochemical research.
Formula:C7H10O4
InChI:InChI=1S/C7H10O4/c1-5(8)4-6(9)2-3-7(10)11/h2-4H2,1H3,(H,10,11)
InChI key:InChIKey=WYEPBHZLDUPIOD-UHFFFAOYSA-N
SMILES:C(CCC(O)=O)(CC(C)=O)=O
Synonyms:- Ccris 1387
- Heptanoic acid, 4,6-dioxo-
- Nsc 174804
- Succinyl acetone
- Succinylacetone
- 4,6-Dioxoheptanoic acid
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Found 8 products.
4,6-Dioxoheptanoic acid
CAS:<p>4,6-Dioxoheptanoic acid (Succinylacetone) acts as a potent inhibitor of heme biosynthesis.</p>Formula:C7H10O4Purity:97.18% - ≥98%Color and Shape:PowderMolecular weight:158.15Succinylacetone
CAS:<p>Applications Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.<br>References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),<br></p>Formula:C7H10O4Color and Shape:White To Off-WhiteMolecular weight:158.15Succinylacetone-13C7
CAS:<p>Applications Succinylacetone-13C7 is a labelled analogue of Succinylacetone (S692060). Succinylacetone (SA) is a specific marker for the inherited metabolic disease, hepatorenal tyrosinemia. It was developed a stable-isotope for the determination of SA in dried blood spots (DBS) and liquid urine using a 13C4-SA as internal standard. The method was applied retrospectively and prospectively for the diagnosis of hepatorenal tyrosinemia and for follow-up of patients under treatment.<br>References Kvittingen, E., et al.: Inher. Metab. Dis., 14, 554 (1991), Lindstedt, S., et al.: Lancet, 340, 813 (1992), Schulze, A., et al.: Clin. Chem., 47, 1424 (2001), Allard, P., et al.: Clin. Biochem., 37, 1010 (2004),<br></p>Formula:C7H10O4Color and Shape:NeatMolecular weight:158.15
