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CAS 51581-32-9

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Norpyridostigmine

Description:
Norpyridostigmine is a chemical compound classified as a reversible inhibitor of the enzyme acetylcholinesterase, which plays a crucial role in the breakdown of the neurotransmitter acetylcholine. This inhibition leads to increased levels of acetylcholine in the synaptic cleft, enhancing cholinergic transmission. Norpyridostigmine is structurally related to pyridostigmine, differing primarily in its chemical modifications. It is often studied for its potential therapeutic applications, particularly in conditions such as myasthenia gravis and certain types of nerve agent exposure. The compound is typically administered in a pharmaceutical context and may exhibit side effects common to cholinesterase inhibitors, including gastrointestinal disturbances and increased salivation. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. As with any chemical substance, handling Norpyridostigmine requires adherence to safety protocols to mitigate risks associated with exposure.
Formula:C8H10N2O2
InChI:InChI=1S/C8H10N2O2/c1-10(2)8(11)12-7-4-3-5-9-6-7/h3-6H,1-2H3
InChI key:InChIKey=VZELUFSMNDBCBO-UHFFFAOYSA-N
SMILES:O(C(N(C)C)=O)C=1C=CC=NC1
Synonyms:
  • 3-(Dimethylcarbamoyloxy)pyridine
  • 3-Pyridyl dimethylcarbamate
  • Carbamic acid, N,N-dimethyl-, 3-pyridinyl ester
  • Carbamic acid, dimethyl-, 3-pyridinyl ester
  • Carbamic acid, dimethyl-, 3-pyridyl ester
  • NSC 168373
  • Norpyridostigmine
  • Pyridin-3-Yl Dimethylcarbamate
  • Ro 1-5142
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