CAS 51598-60-8

Cimetropium bromide

Description:

Cimetropium bromide is a synthetic quaternary ammonium compound primarily used as an antispasmodic agent. It is characterized by its ability to inhibit smooth muscle contractions, making it effective in treating gastrointestinal disorders such as irritable bowel syndrome. The compound functions as a muscarinic receptor antagonist, which helps to reduce spasms in the digestive tract. Cimetropium bromide is typically administered in oral form and is known for its relatively low side effect profile compared to other antispasmodics. Its chemical structure includes a bromide ion, which contributes to its solubility and bioavailability. The substance is generally well-tolerated, but like all medications, it may cause side effects in some individuals, including dry mouth or blurred vision. Due to its specific mechanism of action, Cimetropium bromide is often preferred in clinical settings where a targeted approach to managing gastrointestinal motility is required. As with any pharmaceutical, it is essential to use Cimetropium bromide under medical supervision to ensure safety and efficacy.

Formula: C₂₁H₂₈BrNO₄

InChI: InChI=1/C21H28NO4.BrH/c1-22(11-13-7-8-13)17-9-15(10-18(22)20-19(17)26-20)25-21(24)16(12-23)14-5-3-2-4-6-14;/h2-6,13,15-20,23H,7-12H2,1H3;1H/q+1;/p-1/t15?,16-,17-,18-,19-,20+,22?;/m0./s1

InChI key: InChIKey=WDURTRGFUGAJHA-GSWUYBTGSA-M

SMILES: C([N+]1(C)[C@]2([C@@]3([C@@](O3)([C@@]1(C[C@H](OC([C@H](CO)C4=CC=CC=C4)=O)C2)[H])[H])[H])[H])C5CC5.[Br-]

Synonyms:

• (1S,2R,4S,5S)-9-(cyclopropylmethyl)-7-{[(2R)-3-hydroxy-2-phenylpropanoyl]oxy}-9-methyl-3-oxa-9-azoniatricyclo[3.3.1.0~2,4~]nonane bromide
• (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-9-(Cyclopropylmethyl)-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-3-oxa-9-azoniatricyclo(3.3.1.0(sup 2,4))nonane bromide
• 3-Oxa-9-azatricyclo[3.3.1.0^2,4]nonane, 3-oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane deriv.
• 3-Oxa-9-azoniatricyclo(3.3.1.0(2,4))nonane, 9-(cyclopropylmethyl)-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, (7(S)-(1alpha,2beta,4beta,5alpha,7beta))-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-(cyclopropylmethyl)-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, [7(S)-(1α,2β,4β,5α,7β)]-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.0^2,4]nonane, 9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1α,2β,4β,5α,7β)-
• 8-(Cyclopropylmethyl)-6beta,7beta-epoxy-3alpha-((S)-tropoyl)-1alphaH,5alphaH-tropanium bromid
• 8-(Cyclopropylmethyl)-6beta,7beta-epoxy-3alpha-hydroxy-1alphaH,5alphaH-tropanium bromide, (-)-(S)-tropate
• Alginor
• Bromure de cimetropium
• Bromure de cimetropium [French]
• Bromuro de cimetropio
• Bromuro de cimetropio [Spanish]
• Cimetropii bromidum
• Cimetropii bromidum [Latin]
• Cimetropium bromide [INN]
• Da 3177
• N-Cyclopropylmethylscopolamine bromide
• Unii-0C7M5We60Q
• 3-Oxa-9-azatricyclo[3.3.1.02,4]nonane, 3-oxa-9-azoniatricyclo[3.3.1.02,4]nonane deriv.
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1α,2β,4β,5α,7β)-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-(cyclopropylmethyl)-7-(3-hydroxy-1-oxo-2-phenylpropoxy)-9-methyl-, bromide, [7(S)-(1α,2β,4β,5α,7β)]-
• 3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane, 9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide (1:1), (1α,2β,4β,5α,7β)-
• Cimetronin bromide
• Cimetropium
• da3177
• CIMETROPIUM BROMIDE
• N-Cyclopropvlmethylscopolamine bromide
• Cimetropiumbromid

3-Oxa-9-azoniatricyclo[3.3.1.02,4]nonane,9-(cyclopropylmethyl)-7-[(2S)-3-hydroxy-1-oxo-2-phenylpropoxy]-9-methyl-, bromide, (1a,2b,4b,5a,7b)-

CAS: 51598-60-8

Formula: C₂₁H₂₈BrNO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 438.3553

Ref: IN-DA01CB77

Cimetropium bromide

CAS: 51598-60-8

Formula: C₂₁H₂₈BrNO₄

Molecular weight: 438.36

Ref: 7W-GP9961

Cimetropium bromide

CAS: 51598-60-8

Cimetropium bromide is a pharmacological agent that binds to muscarinic receptors, inhibiting the release of acetylcholine. It is used in the treatment of bowel disease, such as constipation and irritable bowel syndrome. Cimetropium bromide has been shown to be effective in treating symptoms of these diseases, including decreased intestinal motility, increased stool consistency, and relief from abdominal pain. Cimetropium bromide has also been found to be effective in reducing symptoms of inflammatory bowel disease. This drug inhibits the release of acetylcholine by binding with muscarinic receptors on the smooth muscle cells lining the intestine and bladder. Cimetropium bromide is a potent antimuscarinic agent that can cause dry mouth and blurred vision.

Formula: C₂₁H₂₈BrNO₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 438.36 g/mol

Ref: 3D-FC152009

Cimetropium Bromide

Controlled Product

CAS: 51598-60-8

Formula: C₂₁H₂₈NO₄·Br

Color and Shape: Neat

Molecular weight: 438.36

Ref: TR-C441685

Cimetropium Bromide-d4

Controlled Product

CAS: 51598-60-8

Formula: C₂₁H₂₄D₄BrNO₄

Color and Shape: Neat

Molecular weight: 442.38

Ref: TR-C441687

Cimetropium Bromide

CAS: 51598-60-8

Cimetropium Bromide is a mAChR antagonist used for long-term treatment of irritable bowel syndrome.

Formula: C₂₁H₂₈BrNO₄

Color and Shape: Solid

Molecular weight: 438.36

Ref: TM-T14966