CAS 516-05-2
:Methylmalonic acid
Description:
Methylmalonic acid (MMA) is a dicarboxylic acid with the chemical formula C5H8O4 and a CAS number of 516-05-2. It is a colorless, crystalline solid that is soluble in water and polar organic solvents. MMA is characterized by the presence of two carboxylic acid groups (-COOH) and a branched carbon chain, which contributes to its reactivity and biological significance. It plays a crucial role in metabolism, particularly in the conversion of certain amino acids and fatty acids, and is a key intermediate in the metabolism of vitamin B12. Elevated levels of methylmalonic acid in the body can indicate a deficiency in vitamin B12, leading to various metabolic disorders. In addition to its biological importance, methylmalonic acid is also used in organic synthesis and as a building block for various chemical compounds. Its derivatives have applications in pharmaceuticals and materials science, highlighting its versatility in both biological and industrial contexts.
Formula:C4H6O4
InChI:InChI=1/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/p-2
InChI key:InChIKey=ZIYVHBGGAOATLY-UHFFFAOYSA-N
SMILES:C(C(O)=O)(C(O)=O)C
Synonyms:- 1,1-Ethanedicarboxylic acid
- 2-Methylmalonic acid
- 2-Methylpropanedioic acid
- Acide Methylmalonique
- Acido Metilmalonico
- Isosuccinic acid
- Malonic acid, methyl-
- Methylmalonic Acid
- Methylmalonsaeure
- Methylpropanedioic acid
- Nsc 25201
- Propanedioic acid, 2-methyl-
- Propanedioic acid, methyl-
- 3-methoxy-3-oxopropanoic acid
- methylpropanedioate
- Methylmalonicacid
- Methyl (Ethoxy Methylene) Cyanoacetate
- isosuccinicacid
- Methylmalonic
- methyl-malonicaci
- 2-methylmalonicacid
- 1,1-ethanedicarboxylicacid
- See more synonyms
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Found 10 products.
Methylmalonic Acid
CAS:Formula:C4H6O4Purity:>98.0%(T)Color and Shape:White to Almost white powder to crystalMolecular weight:118.09Methylmalonic acid
CAS:<p>Methylmalonic acid</p>Purity:97%Color and Shape:SolidMolecular weight:118.09g/mol2-Methylmalonic acid 100 µg/mL in Acetonitrile
CAS:Formula:C4H6O4Color and Shape:Single SolutionMolecular weight:118.09Methylmalonic acid
CAS:<p>Methylmalonic acid (Isosuccinic acid) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A.</p>Formula:C4H6O4Purity:98%Color and Shape:SolidMolecular weight:118.09Methylmalonic Acid
CAS:Controlled Product<p>Applications Binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.<br>References Pedersen, T., et al.: J. Chromatogr., B: Anal. Technol. Biomed. Life Sci., 879, 1502 (2011),<br></p>Formula:C4H6O4Color and Shape:NeatMolecular weight:118.09Methylmalonic acid
CAS:<p>Methylmalonic acid is a metabolite of the vitamin B12. It is formed from homocysteine via the enzyme methylmalonyl-CoA mutase, which converts it to methylmalonic acid. Methylmalonic acid can be detected in the blood and urine and is used as a diagnostic tool for metabolic diseases such as bowel disease and cobalamin deficiency. The rate constant (k) for the conversion of methylmalonic acid to methylmalonate has been determined by gas chromatography with mass spectrometry analysis. The analytical method involves derivatization with an organic solvent, followed by chromatographic analysis. This compound has been shown to cause neuronal death in rats and may lead to peripheral neuropathy in humans.</p>Formula:C4H6O4Color and Shape:PowderMolecular weight:118.09 g/molMethylmalonic acid
CAS:Formula:C4H6O4Purity:95%Color and Shape:Solid, CrystallineMolecular weight:118.088Ref: 10-F080319
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