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CAS 516-05-2

:

Methylmalonic acid

Description:
Methylmalonic acid (MMA) is a dicarboxylic acid with the chemical formula C5H8O4 and a CAS number of 516-05-2. It is a colorless, crystalline solid that is soluble in water and polar organic solvents. MMA is characterized by the presence of two carboxylic acid groups (-COOH) and a branched carbon chain, which contributes to its reactivity and biological significance. It plays a crucial role in metabolism, particularly in the conversion of certain amino acids and fatty acids, and is a key intermediate in the metabolism of vitamin B12. Elevated levels of methylmalonic acid in the body can indicate a deficiency in vitamin B12, leading to various metabolic disorders. In addition to its biological importance, methylmalonic acid is also used in organic synthesis and as a building block for various chemical compounds. Its derivatives have applications in pharmaceuticals and materials science, highlighting its versatility in both biological and industrial contexts.
Formula:C4H6O4
InChI:InChI=1/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/p-2
InChI key:InChIKey=ZIYVHBGGAOATLY-UHFFFAOYSA-N
SMILES:C(C(O)=O)(C(O)=O)C
Synonyms:
  • 1,1-Ethanedicarboxylic acid
  • 2-Methylmalonic acid
  • 2-Methylpropanedioic acid
  • Acide Methylmalonique
  • Acido Metilmalonico
  • Isosuccinic acid
  • Malonic acid, methyl-
  • Methylmalonic Acid
  • Methylmalonsaeure
  • Methylpropanedioic acid
  • See more synonyms
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Found 10 products.
  • Methylmalonic Acid

    CAS:
    Formula:C4H6O4
    Purity:>98.0%(T)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:118.09

    Ref: 3B-M0568

    25g
    51.00€
    100g
    175.00€
  • 2-Methylmalonic acid

    CAS:
    Formula:C4H6O4
    Purity:97%
    Color and Shape:Solid
    Molecular weight:118.0880

    Ref: IN-DA003S46

    5g
    26.00€
    10g
    30.00€
    25g
    28.00€
    50g
    50.00€
    100g
    62.00€
    500g
    162.00€
  • Methylmalonic acid

    CAS:
    Methylmalonic acid
    Purity:≥95%
    Molecular weight:118.09g/mol

    Ref: 54-BUP18432

    1g
    52.00€
    2g
    63.00€
    5g
    83.00€
  • Methylmalonic acid

    CAS:
    <p>Methylmalonic acid</p>
    Purity:97%
    Color and Shape:Solid
    Molecular weight:118.09g/mol

    Ref: 54-OR911347

    5g
    32.00€
    25g
    36.00€
    100g
    74.00€
    500g
    286.00€
    2.5kg
    1,240.00€
  • 2-Methylmalonic acid 100 µg/mL in Acetonitrile

    CAS:
    Formula:C4H6O4
    Color and Shape:Single Solution
    Molecular weight:118.09

    Ref: 04-A15089080AL-100

    1ml
    To inquire
  • Methylmalonic Acid

    CAS:
    Formula:C4H6O4
    Molecular weight:118.09

    Ref: 4Z-M-213001

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Methylmalonic acid

    CAS:
    <p>Methylmalonic acid (Isosuccinic acid) is a dicarboxylic acid that can be derived from methylmalonyl-coenzyme A.</p>
    Formula:C4H6O4
    Purity:98%
    Color and Shape:Solid
    Molecular weight:118.09
  • Methylmalonic Acid

    Controlled Product
    CAS:
    <p>Applications Binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.<br>References Pedersen, T., et al.: J. Chromatogr., B: Anal. Technol. Biomed. Life Sci., 879, 1502 (2011),<br></p>
    Formula:C4H6O4
    Color and Shape:Neat
    Molecular weight:118.09

    Ref: TR-M318860

    1g
    105.00€
    5g
    115.00€
    50mg
    97.00€
  • Methylmalonic acid

    CAS:
    <p>Methylmalonic acid is a metabolite of the vitamin B12. It is formed from homocysteine via the enzyme methylmalonyl-CoA mutase, which converts it to methylmalonic acid. Methylmalonic acid can be detected in the blood and urine and is used as a diagnostic tool for metabolic diseases such as bowel disease and cobalamin deficiency. The rate constant (k) for the conversion of methylmalonic acid to methylmalonate has been determined by gas chromatography with mass spectrometry analysis. The analytical method involves derivatization with an organic solvent, followed by chromatographic analysis. This compound has been shown to cause neuronal death in rats and may lead to peripheral neuropathy in humans.</p>
    Formula:C4H6O4
    Color and Shape:Powder
    Molecular weight:118.09 g/mol

    Ref: 3D-FM25870

    1kg
    1,036.00€
    2kg
    1,518.00€
    100g
    255.00€
    250g
    478.00€
    500g
    683.00€
  • Methylmalonic acid

    CAS:
    Formula:C4H6O4
    Purity:95%
    Color and Shape:Solid, Crystalline
    Molecular weight:118.088

    Ref: 10-F080319

    5g
    13.00€
    10g
    14.00€
    15g
    20.00€
    1kg
    459.00€
    25g
    21.00€
    50g
    36.00€
    100g
    65.00€
    250g
    137.00€
    500g
    252.00€