CymitQuimica logo

CAS 516-12-1

:

N-Iodosuccinimide

Description:
N-Iodosuccinimide (NIS) is an organic compound with the molecular formula C4H4N2O2I. It is a white to pale yellow crystalline solid that is primarily used as a reagent in organic synthesis, particularly for the iodination of various substrates. NIS is known for its mild and selective oxidizing properties, making it valuable in the preparation of iodinated compounds. The compound is soluble in polar solvents such as water and methanol, but less soluble in non-polar solvents. N-Iodosuccinimide is often utilized in reactions involving alkenes, alcohols, and aromatic compounds, facilitating the introduction of iodine into organic molecules. Additionally, it can serve as a source of iodine in radical reactions and is employed in the synthesis of pharmaceuticals and agrochemicals. Due to its reactivity, NIS should be handled with care, as it can be hazardous if ingested or inhaled, and appropriate safety measures should be taken during its use in laboratory settings.
Formula:C4H4INO2
InChI:InChI=1/C4H4INO2/c5-6-3(7)1-2-4(6)8/h1-2H2
InChI key:InChIKey=LQZMLBORDGWNPD-UHFFFAOYSA-N
SMILES:IN1C(=O)CCC1=O
Synonyms:
  • 1-Iodo-2,5-Pyrrolidinedione
  • 1-Iodo-5-Pyrrolidinedione
  • 1-Iodopyrrolidine-2,5-Dione
  • 2,5-Pyrrolidinedione, 1-iodo-
  • Iodosuccinimide
  • N-Iodo-Succinimid
  • NIS
  • Succinimide,N-iodo-
  • Succiniodimide
  • N-Iodosuccinimide
  • See more synonyms
Sort by

Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 9 products.
  • N-Iodosuccinimide

    CAS:
    Formula:C4H4INO2
    Purity:>99.0%(T)
    Color and Shape:White to Light yellow to Light orange powder to crystal
    Molecular weight:224.99

    Ref: 3B-I0074

    5g
    45.00€
    25g
    116.00€
    100g
    298.00€
  • N-Iodosuccinimide, 97%

    CAS:
    <p>N-Iodosuccinimide is used in the preparation of vinyl sulfones from olefins and benzenesulfinic acid. It acts as a source for I+ and involved in Hunsdiecker reactions for the conversion of cinnamic acids, and propiolic acids to the corresponding alfa-halostyrenes and 1-halo-1-alkynes respectively.</p>
    Formula:C4H4INO2
    Purity:97%
    Color and Shape:Crystals or powder or crystalline powder., White to yellow to brown
    Molecular weight:224.99

    Ref: 02-A14320

    5g
    52.00€
    25g
    136.00€
    100g
    393.00€
  • N-Iodosuccinimide

    CAS:
    Formula:C4H4INO2
    Purity:97%
    Color and Shape:Solid
    Molecular weight:224.9845

    Ref: IN-DA0035TM

    5g
    To inquire
    10g
    26.00€
    25g
    28.00€
    50g
    44.00€
    100g
    55.00€
    500g
    159.00€
  • N-Iodosuccinimide

    CAS:
    N-Iodosuccinimide
    Formula:C4H4INO2
    Purity:98%
    Color and Shape: faint brown powder
    Molecular weight:224.98453g/mol

    Ref: 54-OR28900

    25g
    37.00€
    100g
    58.00€
    500g
    166.00€
  • N-Iodosuccinimide

    CAS:
    Formula:C4H4INO2
    Purity:98.0%
    Color and Shape:Crystalline Powder
    Molecular weight:224.985

    Ref: 10-F003418

    5g
    9.00€
    10g
    12.00€
    1kg
    258.00€
    25g
    14.00€
    50g
    25.00€
    5kg
    837.00€
    100g
    36.00€
    250g
    83.00€
    500g
    144.00€
  • N-Iodosuccinimide

    CAS:
    Formula:C4H4INO2
    Purity:98.0 - 102.0 %
    Color and Shape:White to pale yellow crystalline powder
    Molecular weight:224.99

    Ref: 7W-GK8008

    5g
    26.00€
    25g
    79.00€
    100g
    185.00€
  • N-Iodosuccinimide

    CAS:
    <p>N-Iodosuccinimide is a reagent that is used in the synthesis of monoclonal antibodies. It reacts with the amino groups of proteins to form stable complexes that are soluble in organic solvents. N-Iodosuccinimide can also be used for the treatment of tumors by reacting with DNA to form cross-links and inhibiting tumor cell growth. N-Iodosuccinimide reacts with methyl ketones to form mixtures of stable complexes, which are useful for the synthesis of polymers and polyesters. This reaction mechanism is a variation on the Suzuki coupling reaction and has been shown to be effective for cervical cancer cells in culture.</p>
    Formula:C4H4INO2
    Color and Shape:Brown Clear Liquid
    Molecular weight:224.98 g/mol

    Ref: 3D-FI07623

    1kg
    636.00€
    2kg
    844.00€
    5kg
    1,136.00€
    250g
    279.00€
    500g
    429.00€
  • N-Iodosuccinimide extrapure, 99%

    CAS:
    Formula:C4H4INO2
    Purity:min. 99.0%
    Color and Shape:Off-white to yellow to tan, Crystalline powder
    Molecular weight:224.98

    Ref: SR-70031

    5g
    28.00€
    25g
    31.00€
    100g
    60.00€
  • N-Iodosuccinimide

    Controlled Product
    CAS:
    <p>Applications N-Iodosuccinimide is a iodo substituted succinimide that is used as an iodinating agent in chemical synthesis.<br>References Castanet, A.-S. et al.: Tetrahed. Lett., 43, 5047 (2002);<br></p>
    Formula:C4H4INO2
    Color and Shape:Neat
    Molecular weight:224.99

    Ref: TR-I719900

    5g
    79.00€
    10g
    150.00€
    25g
    216.00€