CAS 516-15-4
:Pregn-4-ene-3,11,20-trione
Description:
Pregn-4-ene-3,11,20-trione, commonly known as progesterone, is a steroid hormone that plays a crucial role in the menstrual cycle, pregnancy, and embryogenesis in humans and other species. It is characterized by its structure, which includes a steroid backbone with three ketone groups at positions 3, 11, and 20. This compound is typically a white crystalline solid and is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Progesterone is synthesized in the ovaries, placenta, and adrenal glands and is essential for maintaining the early stages of pregnancy by preparing the endometrium for implantation and inhibiting uterine contractions. It also plays a role in regulating various physiological processes, including the menstrual cycle and the development of mammary glands. Due to its biological significance, progesterone is used therapeutically in hormone replacement therapy and in the treatment of various reproductive health issues. Its CAS number, 516-15-4, is a unique identifier that facilitates the identification and study of this important hormone in scientific literature and databases.
Formula:C21H28O3
InChI:InChI=1S/C21H28O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-17,19H,4-9,11H2,1-3H3/t15-,16+,17-,19+,20-,21+/m0/s1
InChI key:InChIKey=WKAVAGKRWFGIEA-DADBAOPHSA-N
SMILES:C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3=O)[C@@H](C(C)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]
Synonyms:- 11-Ketoprogesterone
- 11-Oxopregn-4-ene-3,20-dione
- 11-Oxoprogesterone
- 4-Pregnene-3,11,20-trione
- Dg 322A
- Ketogestin
- Ketoprogesterone
- Pregn-4-Ene-3,11,20-Trione
- Stx 124
- U 1258
- Δ<sup>4</sup>-Pregnene-3,11,20-trione
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Found 9 products.
4-Pregnene-3,11,20-trione
CAS:Formula:C21H28O3Purity:>97.0%(HPLC)Color and Shape:White to Dark green powder to crystalMolecular weight:328.4511-Ketoprogesterone
CAS:Controlled ProductFormula:C21H28O3Color and Shape:NeatMolecular weight:328.45Ketogestin
CAS:Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.Formula:C21H28O3Purity:99.19%Color and Shape:SolidMolecular weight:328.4511-Ketoprogesterone
CAS:Controlled Product<p>Applications 11-Ketoprogesterone is a metabolite of Progesterone which is a steroid hormone Inducing maturation and secretory activity of the uterine endothelium. Progesterone is implicated in the etiology of breast cancer.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),<br></p>Formula:C21H28O3Color and Shape:NeatMolecular weight:328.454-Pregnene-3,11,20-trione
CAS:Controlled Product<p>4-Pregnene-3,11,20-trione is a steroid that is a synthetic form of the natural hormone progesterone. The hydroxyl group on 4-pregnene-3,11,20-trione allows it to bind to the mineralocorticoid receptor (MR) and have inhibitory properties. 4-Pregnene-3,11,20-trione has been shown to prevent tumor growth in vitro and in vivo. It is also known to have physiological effects in lung cells such as alveolar type II cells and cancer tissue. This molecule can be used as a model system for studying the effects of steroids on cancer cells and for investigating the relationship between biochemical activity and cell proliferation.</p>Formula:C21H28O3Purity:Min. 95%Molecular weight:328.45 g/mol
