CAS 516-15-4

Pregn-4-ene-3,11,20-trione

Description:

Pregn-4-ene-3,11,20-trione, commonly known as progesterone, is a steroid hormone that plays a crucial role in the menstrual cycle, pregnancy, and embryogenesis in humans and other species. It is characterized by its structure, which includes a steroid backbone with three ketone groups at positions 3, 11, and 20. This compound is typically a white crystalline solid and is soluble in organic solvents such as ethanol and chloroform but has limited solubility in water. Progesterone is synthesized in the ovaries, placenta, and adrenal glands and is essential for maintaining the early stages of pregnancy by preparing the endometrium for implantation and inhibiting uterine contractions. It also plays a role in regulating various physiological processes, including the menstrual cycle and the development of mammary glands. Due to its biological significance, progesterone is used therapeutically in hormone replacement therapy and in the treatment of various reproductive health issues. Its CAS number, 516-15-4, is a unique identifier that facilitates the identification and study of this important hormone in scientific literature and databases.

Formula: C₂₁H₂₈O₃

InChI: InChI=1S/C21H28O3/c1-12(22)16-6-7-17-15-5-4-13-10-14(23)8-9-20(13,2)19(15)18(24)11-21(16,17)3/h10,15-17,19H,4-9,11H2,1-3H3/t15-,16+,17-,19+,20-,21+/m0/s1

InChI key: InChIKey=WKAVAGKRWFGIEA-DADBAOPHSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3=O)[C@@H](C(C)=O)CC4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• 11-Ketoprogesterone
• 11-Oxopregn-4-ene-3,20-dione
• 11-Oxoprogesterone
• 4-Pregnene-3,11,20-trione
• Dg 322A
• Ketogestin
• Ketoprogesterone
• Pregn-4-Ene-3,11,20-Trione
• Stx 124
• U 1258
• Δ⁴-Pregnene-3,11,20-trione

4-Pregnene-3,11,20-trione

CAS: 516-15-4

Formula: C₂₁H₂₈O₃

Purity: >97.0%(HPLC)

Color and Shape: White to Dark green powder to crystal

Molecular weight: 328.45

Ref: 3B-P0771

11-KETOPROGESTERONE

CAS: 516-15-4

Formula: C₂₁H₂₈O₃

Purity: %

Color and Shape: Solid

Molecular weight: 328.4452

Ref: IN-DA00DEOZ

11-Keto Progesterone

CAS: 516-15-4

Formula: C₂₁H₂₈O₃

Color and Shape: Off-White Solid

Molecular weight: 328.45

Ref: 4Z-P-3252

Ketogestin

CAS: 516-15-4

Ketogestin

Purity: ≥98%

Molecular weight: 328.45g/mol

Ref: 54-BUP20900

11-Ketoprogesterone

Controlled Product

CAS: 516-15-4

Formula: C₂₁H₂₈O₃

Color and Shape: Neat

Molecular weight: 328.45

Ref: 86-MM0222.12

Ketogestin

CAS: 516-15-4

Ketogestin is a progestational steroid and an inhibitor of enzyme 11β-hydroxysteroid dehydrogenase, and a weak negative modulator of GABAA receptors.

Formula: C₂₁H₂₈O₃

Purity: 99.19%

Color and Shape: Solid

Molecular weight: 328.45

Ref: TM-T67094

11-Ketoprogesterone

Controlled Product

CAS: 516-15-4

Applications 11-Ketoprogesterone is a metabolite of Progesterone which is a steroid hormone Inducing maturation and secretory activity of the uterine endothelium. Progesterone is implicated in the etiology of breast cancer.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Anderson, E., et al.: Breast Cancer Res., 4, 197 (2002), Lanari, C., et al.: Breast Cancer Res., 4, 240 (2002), Albrecht, E.D., et al.: Front. Biosci., 8, 416 (2003), Qiu, M., et al.: J. Steroid Biochem. Mol. Biol., 85, 147 (2003),

Formula: C₂₁H₂₈O₃

Color and Shape: Neat

Molecular weight: 328.45

Ref: TR-K201000

4-Pregnene-3,11,20-trione

Controlled Product

CAS: 516-15-4

4-Pregnene-3,11,20-trione is a steroid that is a synthetic form of the natural hormone progesterone. The hydroxyl group on 4-pregnene-3,11,20-trione allows it to bind to the mineralocorticoid receptor (MR) and have inhibitory properties. 4-Pregnene-3,11,20-trione has been shown to prevent tumor growth in vitro and in vivo. It is also known to have physiological effects in lung cells such as alveolar type II cells and cancer tissue. This molecule can be used as a model system for studying the effects of steroids on cancer cells and for investigating the relationship between biochemical activity and cell proliferation.

Formula: C₂₁H₂₈O₃

Purity: Min. 95%

Molecular weight: 328.45 g/mol

Ref: 3D-AAA51615

11-Keto Progesterone

CAS: 516-15-4

Formula: C₂₁H₂₈O₃

Molecular weight: 328.45

Ref: ST-EA-CP-P133073