CAS 516-50-7

Taurodeoxycholic acid

Description:

Taurodeoxycholic acid (TDCA) is a bile acid derivative that plays a significant role in the digestion and absorption of fats and fat-soluble vitamins in the intestine. It is a conjugated bile acid, formed by the conjugation of deoxycholic acid with the amino acid taurine. TDCA is characterized by its amphipathic nature, possessing both hydrophilic and hydrophobic properties, which allows it to effectively emulsify fats. This compound is typically found in the bile of various mammals and is involved in the regulation of cholesterol metabolism and intestinal motility. Additionally, TDCA has been studied for its potential therapeutic effects, including its role in modulating gut microbiota and its implications in liver health. Its chemical structure includes a steroid nucleus with hydroxyl groups, contributing to its biological activity. As a bile acid, TDCA is also involved in signaling pathways that influence metabolic processes. Overall, taurodeoxycholic acid is an important substance in both digestive physiology and potential clinical applications.

Formula: C₂₆H₄₅NO₆S

InChI: InChI=1S/C26H45NO6S/c1-16(4-9-24(30)27-12-13-34(31,32)33)20-7-8-21-19-6-5-17-14-18(28)10-11-25(17,2)22(19)15-23(29)26(20,21)3/h16-23,28-29H,4-15H2,1-3H3,(H,27,30)(H,31,32,33)/t16-,17-,18-,19+,20-,21+,22+,23+,25+,26-/m1/s1

InChI key: InChIKey=AWDRATDZQPNJFN-VAYUFCLWSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@](CC3)(C[C@H](O)CC4)[H])(C[C@@H]1O)[H])[H])(CC[C@@]2([C@@H](CCC(NCCS(=O)(=O)O)=O)C)[H])[H]

Synonyms:

• 2-[[(3α,5β,12α)-3,12-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonic acid
• 3α,12α-Dihydroxy-5β-cholanic acid-24-taurine
• Cholane, ethanesulfonic acid deriv.
• Deoxycholyltaurine
• Deoxytaurocholic acid
• Ethanesulfonic acid, 2-(((3alpha,5beta,12alpha)-3,12-dihydroxy-24-oxocholan-24-yl)amino)-
• Ethanesulfonic acid, 2-[[(3α,5β,12α)-3,12-dihydroxy-24-oxocholan-24-yl]amino]-
• N-(3a,12a-dihydroxy-5b-cholan-24-oyl)-Taurine
• Taurine, N-(3α,12α-dihydroxy-5β-cholan-24-oyl)-
• Taurodeoxycholic acid
• Taurodesoxycholic acid
• Tudcabil

Taurodeoxycholic acid

CAS: 516-50-7

Taurodeoxycholic acid

Purity: ≥98%

Molecular weight: 499.7g/mol

Ref: 54-BUP06967

Taurodeoxycholic Acid

CAS: 516-50-7

Formula: C₂₆H₄₅NO₆S

Color and Shape: White To Off-White Solid

Molecular weight: 499.71

Ref: 4Z-C-575

Taurodeoxycholic acid

CAS: 516-50-7

Taurodeoxycholic acid: bile acid, stabilizes mitochondria, anti-apoptotic, neuroprotective, used in Huntington's disease research.

Formula: C₂₆H₄₅NO₆S

Purity: 99.22%

Color and Shape: Solid

Molecular weight: 499.7

Ref: TM-T75319

Taurodeoxycholic-d4 Acid

CAS: 516-50-7

Formula: C₂₆H₄₁NO₆SD₄

Molecular weight: 503.74

Ref: 4Z-C-576

Taurodeoxycholic-2,2,3,4,4-d5 Acid (d5 major)

Controlled Product

CAS: 516-50-7

Applications Deoxycholyltaurine rescues human colon cancer cells from apoptosis by activating EGFR-dependent PI3K/Akt signaling.
References Cheng, K., et al.: Biochem. J., 330, 353 (1998), Cheng, K., et al.: Cancer Res., 63, 6744 (2003), Bellacosa, A., et al.: Adv. Cancer Res., 94, 29 (2005), Cheng, K., et al.: Biochem. Pharmacol., 70, 1035 (2005), Fang, D., et al.: J. Biol. Chem., 282, 11221 (2007),

Formula: C₂₆H₄₀D₅NO₆S

Color and Shape: White To Off-White

Molecular weight: 504.73

Ref: TR-T009002