CAS 516-85-8

Dehydroergosterol

Description:

Dehydroergosterol, with the CAS number 516-85-8, is a sterol compound that is a derivative of ergosterol, which is primarily found in fungi and yeast. It is characterized by its unsaturated structure, featuring a double bond in the sterol backbone, which contributes to its unique biological properties. Dehydroergosterol is often used in research as a photoluminescent probe due to its ability to absorb ultraviolet light and emit fluorescence. This compound plays a significant role in studies related to membrane dynamics and lipid bilayer interactions, as it can integrate into cellular membranes and influence their fluidity and permeability. Additionally, dehydroergosterol has been investigated for its potential applications in phototherapy and as a precursor in the synthesis of various bioactive molecules. Its stability and reactivity under different conditions make it a valuable compound in both biochemical research and potential therapeutic applications.

Formula: C₂₈H₄₂O

InChI: InChI=1/C28H42O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h7-10,14,18-20,22,24-25,29H,11-13,15-17H2,1-6H3/b8-7+/t19-,20+,22-,24+,25-,27-,28+/m0/s1

InChI key: InChIKey=QSVJYFLQYMVBDR-CMNOFMQQSA-N

SMILES: C[C@@]12[C@](C=3C([C@]4(C)C(=CC3)C[C@@H](O)CC4)=CC1)(CC[C@@]2([C@@H](/C=C/[C@@H](C(C)C)C)C)[H])[H]

Synonyms:

• (22E)-Ergosta-5,7,9(11),22-tetraen-3β-ol
• (22E,24R)-Ergosta-5,7,9(11),22-tetraen-3β-ol
• (3beta,22E)-ergosta-5,7,9(11),22-tetraen-3-ol
• (3β,22E)-Ergosta-5,7,9(11),22-tetraen-3-ol
• 9(11)-Dehydroergosterol
• Dehydroergosterol
• Ergosta-5,7,9(11),22-Tetraen-3-Beta-Ol
• Ergosta-5,7,9(11),22-tetraen-3-ol, (3β,22E)-
• Ergosta-5,7,9(11),22-tetraenol
• Ergosta-5,7,9(11),22-tetraen-3β-ol
• ERGOSTA-5,7,9(11),22-TETRAEN-3-OL
• DEHYDROERGOSTEROL (DHE)
• ERGOSTA-5,7,9(11),22-TETRAEN-3-OL;DEHYDROERGOSTEROL (DHE)
• ERGOSTA-5,7,9(11),22-TETRAEN-3BETA-OL
• DHE (Dehydroergosterol)
• delta(5,7,9(11)22)-Ergostatetraen-3-ol
• Ergosta-5,7,9(11),22-tetraen-3-ol, (3beta,22E)-
• Ergosta-5,7,9(11),22-tetren-3β-ol

Dehydroergosterol

CAS: 516-85-8

Dehydroergosterol

Purity: 98%

Molecular weight: 394.63g/mol

Ref: 54-OR1075550

Dehydroergosterol

CAS: 516-85-8

Ropinirole (SKF 101468) is a D3/D2 receptor agonist with anti-amyotrophic lateral sclerosis properties.

Formula: C₂₈H₄₂O

Color and Shape: Solid

Molecular weight: 394.63

Ref: TM-T37858

Dehydroergosterol

CAS: 516-85-8

Formula: C₂₈H₄₂O

Molecular weight: 394.64

Ref: 4Z-E-113013

Dehydroergosterol

Controlled Product

CAS: 516-85-8

Stability Light Sensitive
Applications Dehydroergosterol is a fluorescent cholesterol analog useful as a probe in membrane research.
References Mukherjee, S.; et al.: Biophys. J, 75, 1915 (1998)

Formula: C₂₈H₄₂O

Color and Shape: Neat

Molecular weight: 394.63

Ref: TR-D229768

dehydroergosterol (DHE)

Controlled Product

CAS: 516-85-8

Dehydroergosterol, also known as DHE, is a cholesterol derivative that is a pro-apoptotic protein. It has been shown to inhibit the proliferation of cancer cells by binding to the ATP-binding cassette transporter and MCL-1 protein. DHE binds to cholesterol and changes its phase transition temperature from liquid to solid at physiological levels, which may be due to its anti-cancer properties. The pro-apoptotic effect of DHE was demonstrated in a model system using skin cancer cells. This compound also has been shown to have anti-cancer activity against colorectal adenocarcinoma cells in vitro and in vivo.

Formula: C₂₈H₄₂O

Purity: Min. 95%

Molecular weight: 394.63 g/mol

Ref: 3D-AAA51685

DEHYDROERGOSTEROL

CAS: 516-85-8

Formula: C₂₈H₄₂O

Purity: 96%

Color and Shape: Solid

Molecular weight: 394.6325

Ref: IN-DA00DHQ4