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CAS 51627-14-6

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Cefatrizine

Description:
Cefatrizine is a synthetic antibiotic belonging to the cephalosporin class, which is primarily used for its bactericidal properties against a range of Gram-positive and Gram-negative bacteria. It functions by inhibiting bacterial cell wall synthesis, leading to cell lysis and death. Cefatrizine is characterized by its beta-lactam structure, which is essential for its antimicrobial activity. The compound is typically administered orally and is known for its relatively broad spectrum of activity, making it effective in treating various infections, including respiratory and urinary tract infections. Its pharmacokinetics involve absorption in the gastrointestinal tract, with distribution throughout body tissues. The drug is generally well-tolerated, although potential side effects may include gastrointestinal disturbances and allergic reactions, particularly in individuals with a history of penicillin allergies. As with other antibiotics, appropriate use is crucial to minimize the development of antibiotic resistance. Overall, cefatrizine represents an important option in the arsenal of antimicrobial therapies, particularly in settings where cephalosporins are indicated.
Formula:C18H18N6O5S2
InChI:InChI=1S/C18H18N6O5S2/c19-12(8-1-3-10(25)4-2-8)15(26)21-13-16(27)24-14(18(28)29)9(7-31-17(13)24)6-30-11-5-20-23-22-11/h1-5,12-13,17,25H,6-7,19H2,(H,21,26)(H,28,29)(H,20,22,23)/t12-,13-,17-/m1/s1
InChI key:InChIKey=UOCJDOLVGGIYIQ-PBFPGSCMSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C2=O)(SCC1CSC4=CN=NN4)[H]
Synonyms:
  • (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-5-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(2H-1,2,3-triazol-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-8-oxo-3-[(2H-1,2,3-triazol-4-ylsulfanyl)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 1H-1,2,3-Triazole, 5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid deriv.
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-5-ylthio)methyl]-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[amino(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-4-ylthio)methyl]-, [6R-[6α,7β(R*)]]-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylicacid,7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-8-oxo-3-[(1H-1,2,3-triazol-5-ylthio)methyl]-,(6R,7R)-
  • 7-[2-(4-Hydroxyphenyl)-2-Aminoacetamido]-3-(1,2,3-Triazole-4-Ylthio)Methyl-8-Oxo-5-Thia-1-Azabicyclo[4.2.0]Oct-2-Ene-2-Carboxylic Acid
  • 7-[<span class="text-smallcaps">D</span>-α-Amino-α-(4-hydroxyphenyl)acetamido]-3-(1,2,3-triazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid
  • See more synonyms
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Found 5 products.
  • Cefatrizine
    Glentham
    + Info

    Cefatrizine

    CAS:

    Ref: 7W-GA7632

    ne
    To inquire
  • Cefatrizine
    Targetmol
    + Info

    Cefatrizine

    CAS:
    Cefatrizine inhibits eEF-2 kinase, affecting apoptosis, autophagy, and ER stress in cancers.
    Formula:C18H18N6O5S2
    Purity:98%
    Color and Shape:Solid
    Molecular weight:462.5

    Ref: TM-T26973

  • Cefatrizine
    Biosynth
    + Info

    Cefatrizine

    CAS:
    <p>Cefatrizine is a broad-spectrum antibiotic, which is a semisynthetic cephalosporin derived from cephalosporin C, a natural product originating from the fungus Acremonium chrysogenum. It exerts its mode of action through the inhibition of bacterial cell wall synthesis, a critical component for bacterial growth and replication. Specifically, cefatrizine targets and binds to penicillin-binding proteins (PBPs) located inside the bacterial cell wall, leading to the inhibition of peptidoglycan synthesis. This disruption results in cell lysis and ultimately bacterial cell death.</p>
    Formula:C18H18N6O5S2
    Purity:Min. 95%
    Molecular weight:462.5 g/mol

    Ref: 3D-AC37979

    ne
    To inquire
  • Cefatrizine
    TRC
    + Info

    Cefatrizine

    Controlled Product
    CAS:
    <p>Applications Cefatrizine is a new orally administered cephalosporin with excellent activity against gram-positive cocci, inhibiting all except enterococci at minimal inhibitory concentrations below 1 μg/ml.<br>References Harold, C. N., et al.: Antimicrob, Agents. Chemother., 15, 209 (1979); Actor, P.J., et al.: J. Antibiot., 28, 594 (1975); Sharma, R.K., et al.: Asian. J. Biochem. Pharma. Res., 1, 443 (2011);<br></p>
    Formula:C18H18N6O5S2
    Color and Shape:Neat
    Molecular weight:462.503

    Ref: TR-C237575

    50mg
    4,832.00€
  • Cefatrizine-d4
    TRC
    + Info

    Cefatrizine-d4

    Controlled Product
    CAS:
    Formula:C18D4H14N6O5S2
    Color and Shape:Neat
    Molecular weight:466.527

    Ref: TR-C237577

    50mg
    8,684.00€