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CAS 51627-20-4

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Cefaparole

Description:
Cefaparole is a broad-spectrum cephalosporin antibiotic, classified under the beta-lactam antibiotics. It is primarily used to treat various bacterial infections by inhibiting cell wall synthesis in susceptible bacteria, leading to cell lysis and death. Cefaparole exhibits activity against both Gram-positive and Gram-negative bacteria, making it effective for a range of infections. The compound is characterized by its stability against certain beta-lactamases, which are enzymes produced by some bacteria to resist antibiotic effects. Its pharmacokinetic properties include good absorption and distribution in body tissues, although specific details may vary based on formulation and administration route. Common side effects may include gastrointestinal disturbances, allergic reactions, and potential impacts on renal function. As with other antibiotics, it is crucial to use Cefaparole judiciously to minimize the risk of developing antibiotic resistance. Always consult healthcare professionals for appropriate usage and to understand potential interactions with other medications.
Formula:C19H19N5O5S3
InChI:InChI=1/C19H19N5O5S3/c1-8-22-23-19(32-8)31-7-10-6-30-17-13(16(27)24(17)14(10)18(28)29)21-15(26)12(20)9-2-4-11(25)5-3-9/h2-5,12-13,17,25H,6-7,20H2,1H3,(H,21,26)(H,28,29)/t12-,13-,17-/m1/s1
InChI key:InChIKey=SBUCDZYLTRYMFG-PBFPGSCMSA-N
SMILES:C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C2=O)(SCC1CSC4=NN=C(C)S4)[H]
Synonyms:
  • (6R,7R)-7-((R)-2-Amino-2-(p-hydroxyphenyl)acetamido)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-[[(2R)-2-Amino-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{[amino(4-hydroxyphenyl)acetyl]amino}-3-{[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 5-Thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7-((amino(4-hydroxyphenyl)acetyl)amino)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-8-oxo-, (6R-(6alpha,7beta(R*)))-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2R)-amino(4-hydroxyphenyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, (6R,7R)-
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[amino(4-hydroxyphenyl)acetyl]amino]-3-[[(5-methyl-1,3,4-thiadiazol-2-yl)thio]methyl]-8-oxo-, [6R-[6α,7β(R*)]]-
  • 7-(2-Amino-2-(p-hydroxyphenyl)acetamido)-3-(((5-methyl-1,3,4-thiadiazol-2-yl)thio)methyl)-3-cephem-4-carboxylic acid
  • Cefaparol
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