CAS 5169-78-8

Tipepidine

Description:

Tipepidine, with the CAS number 5169-78-8, is a chemical compound that belongs to the class of piperidine derivatives. It is primarily recognized for its use as an antitussive agent, meaning it is effective in suppressing coughs. Tipepidine exhibits a mechanism of action that involves the modulation of neurotransmitter activity in the central nervous system, which helps alleviate the cough reflex. The compound is typically administered in its hydrochloride salt form, enhancing its solubility and bioavailability. In terms of physical properties, Tipepidine is a white to off-white crystalline powder, and it is soluble in water and alcohol, making it suitable for various pharmaceutical formulations. Its safety profile indicates that it should be used with caution, particularly in individuals with certain medical conditions or those taking specific medications. Overall, Tipepidine is an important compound in the field of respiratory therapeutics, contributing to the management of cough-related symptoms.

Formula: C₁₅H₁₇NS₂

InChI: InChI=1S/C15H17NS2/c1-16-8-2-5-12(11-16)15(13-6-3-9-17-13)14-7-4-10-18-14/h3-4,6-7,9-10H,2,5,8,11H2,1H3

InChI key: InChIKey=JWIXXNLOKOAAQT-UHFFFAOYSA-N

SMILES: C(=C1CN(C)CCC1)(C2=CC=CS2)C3=CC=CS3

Synonyms:

• 3-(Di-2-thienylmethylene)-1-methylpiperidine
• Piperidine, 3-(di-2-thienylmethylene)-1-methyl-
• 3-(Dithien-2-ylmethylene)-1-methylpiperidine
• At 327
• Tipepidine

Tipepidine

CAS: 5169-78-8

Tipepidine: non-narcotic cough suppressant, has antidepressant effects, inhibits DA D2 receptors (IC50=7.0 μM), activates VTA dopamine neurons.

Formula: C₁₅H₁₇NS₂

Color and Shape: Solid

Molecular weight: 275.43

Ref: TM-T60501