CAS 517-28-2: Hematoxylin
Description:Hematoxylin, with the CAS number 517-28-2, is a natural dye derived from the heartwood of the logwood tree (Haematoxylum campechianum). It is primarily used in histology and microscopy as a staining agent, particularly for biological tissues. Hematoxylin exhibits a deep blue to purple color when oxidized, which allows it to effectively bind to nucleic acids, making it valuable for highlighting cell nuclei in tissue samples. The dye is often used in conjunction with eosin, a counterstain, in the widely employed Hematoxylin and Eosin (H&E) staining technique. Hematoxylin is soluble in alcohol and water, and its staining properties can be enhanced through oxidation, typically achieved using agents like sodium iodate or potassium permanganate. In addition to its applications in biological research, hematoxylin has also been explored for potential uses in various fields, including pharmaceuticals and cosmetics, due to its antioxidant properties. However, it is essential to handle hematoxylin with care, as it can be toxic in certain concentrations.
Formula:C16H14O6
InChI:InChI=1S/C16H14O6/c17-10-2-1-8-13-9-4-12(19)11(18)3-7(9)5-16(13,21)6-22-15(8)14(10)20/h1-4,13,17-21H,5-6H2/t13-,16+/m0/s1
InChI key:InChIKey=WZUVPPKBWHMQCE-XJKSGUPXSA-N
SMILES:OC1=CC=C2C(OCC3(O)CC4=CC(O)=C(O)C=C4C23)=C1O
- Synonyms:
- (+)-Hematoxylin
- (6AS,11bR)-7,11b-dihydro-6H-indeno[2,1-c]chromene-3,4,6a,9,10-pentol
- (6aS,11bR)-7,11b-Dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
- 7,11b-Dihydrobenz[b]indeno[1,2-b]pyran-3,4,6a,9,10(6H)-pentol
- Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-
- Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, (6aS-cis)-
- Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, cis-(+)-
- Haematoxylin
- Haematoxyline Powder
- Hematoxilina
- See more synonyms
- Hematoxyline
- Hydroxybrasilin
- Hydroxybrazilin
- Nsc 270085
- Benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, (6aS,11bR)-
- (6aS,11bS)-7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol
- Hematoxylin (C.I. 75290)
- cis-(+)-7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
- hematoxiline
- 517-28-2
- (6aR,11bS)-7,11b-Dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol
- benz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol, 7,11b-dihydro-, (6aR,11bS)-