CAS 517-89-5: Shikonin

Description: Shikonin, with the CAS number 517-89-5, is a natural compound primarily derived from the roots of the plant Lithospermum erythrorhizon, commonly known as purple gromwell. It is a naphthoquinone derivative, characterized by its deep red to purple color, which is attributed to its conjugated double bond system. Shikonin exhibits a range of biological activities, including anti-inflammatory, antimicrobial, and antioxidant properties, making it of interest in both traditional medicine and modern pharmacology. Its mechanism of action involves the modulation of various signaling pathways, contributing to its therapeutic potential. Additionally, shikonin has been studied for its role in wound healing and skin regeneration, as well as its potential use in cancer therapy due to its ability to induce apoptosis in certain cancer cell lines. The compound is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability and application in formulations. Overall, shikonin represents a significant compound in natural product chemistry with promising applications in health and medicine.

Formula: C₁₆H₁₆O₅

InChI: InChI=1S/C16H16O5/c1-8(2)3-4-10(17)9-7-13(20)14-11(18)5-6-12(19)15(14)16(9)21/h3,5-7,10,17-19H,4H2,1-2H3/t10-/m1/s1

InChI key: InChIKey=NEZONWMXZKDMKF-SNVBAGLBSA-N

SMILES: O=C1C=C(C(=O)C=2C(O)=CC=C(O)C12)C(O)CC=C(C)C

Synonyms:

• (R)-(+)-Shikonin
• 1,4-Naphthalenedione 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-
• 1,4-Naphthalenedione, 5,8-Dihydroxy-2-(1-Hydroxy-4-Methyl-3-Penten-1-Yl)-
• 1,4-Naphthalenedione, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (R)-
• 1,4-Naphthalenedione, 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-pentenyl]-
• 1,4-Naphthoquinone, 5,8-dihydroxy-2-(1-hydroxy-4-methyl-3-pentenyl)-, (+)-
• 5,8-Dihydroxy-2-(1-Hydroxy-4-Methylpent-3-En-1-Yl)Naphthalene-1,4-Dione
• 5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)-1,4-naphthoquinone
• 5,8-Dihydroxy-2-[(1R)-1-Hydroxy-4-Methyl-Pent-3-Enyl]Naphthalene-1,4-Dione
• 5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-3-penten-1-yl]-1,4-naphthalenedione
• 5,8-dihydroxy-2-[(1R)-1-hydroxy-4-methylpent-3-en-1-yl]naphthalene-1,4-dione
• Isoarnebin 4
• NSC 252844
• Shikonin S
• Shikonine
• Tokyo Violet
• Shikonin

5,8-Dihydroxy-2-[(1R)-1-hydroxy-4-methyl-pent-3-enyl]naphthalene-1,4-dione

CAS: 517-89-5

• Formula: C₁₆H₁₆O₅
• Purity: 97%
• Color and Shape: Solid
• Molecular weight: 288.2952

Shikonin

CAS: 517-89-5

Shikonin: TMEM16A inhibitor (IC50: 6.5μM), targets PKM2, suppresses NF-κB, inhibits TNF-α, and reduces exosome secretion.

• Formula: C₁₆H₁₆O₅
• Purity: 98.14% - 99.9%
• Color and Shape: Solid
• Molecular weight: 288.3

Shikonin

CAS: 517-89-5

• Color and Shape: Solid
• Molecular weight: 288.30g/mol

Shikonin

CAS: 517-89-5

• Purity: ≥98%
• Molecular weight: 288.3g/mol

Shikonin

CAS: 517-89-5

• Formula: C₁₆H₁₆O₅
• Purity: 95%~99%
• Molecular weight: 288.299

Shikonin

CAS: 517-89-5

• Formula: C₁₆H₁₆O₅
• Molecular weight: 288.30

Shikonin

CAS: 517-89-5

Quinone

• Formula: C₁₆H₁₆O₅
• Purity: ≥ 98.0 % (HPLC)
• Color and Shape: Powder
• Molecular weight: 288.3

(R)-5,8-Dihydroxy-2-(1-hydroxy-4-methylpent-3-en-1-yl)naphthalene-1,4-dione

CAS: 517-89-5

• Purity: 95.0%
• Molecular weight: 288.29901123046875

(R)-(+)-Shikonin

CAS: 517-89-5

• Formula: C₁₆H₁₆O₅
• Color and Shape: Neat
• Molecular weight: 288.30

Shikonin

CAS: 517-89-5

Shikonin is a natural product from the roots of Lithospermum erythroryzon, used in the Chinese …

• Formula: C₁₆H₁₆O₅
• Purity: Min. 98 Area-%
• Color and Shape: Powder
• Molecular weight: 288.3 g/mol